Concepedia

Enzyme Specificity Engineering

Enzyme Specificity Engineering is a biocatalyst engineering strategy that involves the rational or iterative modification of an enzyme’s active site or substrate-binding region to alter its selectivity toward specific substrates, reactions, or stereoisomers, thereby enhancing catalytic precision for targeted biochemical applications.

59

Publications

3.3K

Citations

290

Authors

119

Institutions

Publications per year

2017–2026

20

Parents

Publications

59

Industrial applications of immobilized enzymes—A review

Alessandra Basso, Simona Şerban · Molecular Catalysis · 2019 · 819 citations · Full text

, , +17

Engineering Enzyme Specificity by "Substrate-Assisted Catalysis"

Paul Carter, James A. Wells · Science · 1987 · 225 citations

, , +17

Enzyme engineering: rational redesign versus directed evolution

Ridong Chen · Trends in biotechnology · 2001 · 163 citations

, , +14

Controlling Substrate Specificity and Stereospecificity of Alcohol Dehydrogenases

Christopher M. Nealon, Musa Musa, Jay M. Patel et al. · ACS Catalysis · 2015 · 114 citations

, , +16

Tailoring the Active Site of Chemzymes by Using a Chemogenetic‐Optimization Procedure: Towards Substrate‐Specific Artificial Hydrogenases Based on the Biotin–Avidin Technology

Gérard Klein, Nicolas Humbert, Julieta Gradinaru et al. · Angewandte Chemie International Edition · 2005 · 109 citations

, , +17

1–5 of 59

Authors

290

  1. MR
    Magali Remaud‐Siméon

    Centre National de la Recherche Scientifique, France

    2 publications · 78 citations

    2

    h-index

  2. TR
    Thomas R. Ward

    University of Basel, Switzerland

    2 publications · 147 citations

    2

    h-index

  3. JG
    Julieta Gradinaru

    University of Neuchâtel, Switzerland

    2 publications · 147 citations

    2

    h-index

  4. DD
    David Daudé

    Méditerranée Infection Foundation, France

    2 publications · 68 citations

    2

    h-index

  5. UE
    Untung E. Rusbandi

    University of Neuchâtel, Switzerland

    2 publications · 147 citations

    2

    h-index

1–5 of 290

Institutions

119

  1. Biotechnology Institute

    Washington D.C., United States

    4 h-index

    8 publications

    375 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    22 publications

    982 citations

  3. University of Minnesota

    Minneapolis, United States

    3 h-index

    6 publications

    313 citations

  4. Toulouse Biotechnology Institute, Bio & Chemical Engineering

    Toulouse, France

    3 h-index

    16 publications

    706 citations

  5. National Institute of Advanced Industrial Science and Technology

    Tsukuba, Japan

    3 h-index

    3 publications

    110 citations

  6. University of Massachusetts Amherst

    Amherst Center, United States

    2 h-index

    4 publications

    81 citations

  7. Universitat Politècnica de Catalunya

    Barcelona, Spain

    2 h-index

    7 publications

    205 citations

  8. Barcelona Supercomputing Center

    Barcelona, Spain

    2 h-index

    7 publications

    205 citations

1–8 of 119

Venues

  1. ACS Catalysis

    8 publications · 378 citations

    8

    h-index

  2. Angewandte Chemie International Edition

    4 publications · 258 citations

    4

    h-index

  3. Journal of the American Chemical Society

    JACS · 3 publications · 196 citations

    3

    h-index

  4. Biochemistry

    3 publications · 131 citations

    3

    h-index

  5. Nucleic Acids Research

    2 publications · 37 citations

    2

    h-index

1–5