Concepedia

Enzyme Kinetics Optimization

Enzyme Kinetics Optimization is a methodological framework in enzyme engineering that systematically enhances the catalytic efficiency and substrate specificity of enzymes by iteratively refining kinetic parameters such as turnover number and Michaelis constant through directed evolution or rational design.

97

Publications

4K

Citations

456

Authors

160

Institutions

Publications per year

2017–2026

28

Parents

Publications

97

Ruthenium- and Enzyme-Catalyzed Dynamic Kinetic Resolution of Secondary Alcohols

Björn Persson, Anna Lindhoff Larsson, Mikaël Le Ray et al. · Journal of the American Chemical Society · 1999 · 357 citations

, , +17

A Specific, Highly Active Malate Dehydrogenase by Redesign of a Lactate Dehydrogenase Framework

Helen M. Wilks, Keith Hart, Raymond Feeney et al. · Science · 1988 · 278 citations

, , +17

Dynamic Kinetic Resolution of α-Hydroxy Acid Esters

Fernando F. Huerta, Y. R. Santosh Laxmi, Jan‐E. Bäckvall · Organic Letters · 2000 · 131 citations

, , +17

Medium optimization for a novel 58 kDa dimeric keratinase from Bacillus licheniformis ER-15: Biochemical characterization and application in feather degradation and dehairing of hides

Ekta Tiwary, Rani Gupta · Bioresource Technology · 2010 · 125 citations

, , +16

(<i>S</i>)‐Selective Kinetic Resolution and Chemoenzymatic Dynamic Kinetic Resolution of Secondary Alcohols

Linnéa Borén, Belén Martín‐Matute, Yongmei Xu et al. · Chemistry - A European Journal · 2005 · 116 citations

, , +17

1–5 of 97

Authors

456

  1. JB
    Jan‐E. Bäckvall

    Stockholm University, Sweden

    3 publications · 531 citations

    3

    h-index

  2. JB
    Jan‐E. Bäckvall

    Stockholm University, Sweden

    2 publications · 162 citations

    2

    h-index

  3. TW
    Thomas Wilhelm

    Quadram Institute, United Kingdom

    2 publications · 64 citations

    2

    h-index

  4. AJ
    Alan J. Russell

    University of Pittsburgh, United States

    2 publications · 58 citations

    2

    h-index

  5. VK
    Virendra K. Rathod

    Institute of Chemical Technology, India

    2 publications · 60 citations

    2

    h-index

1–5 of 456

Institutions

160

  1. Stockholm University

    Stockholm, Sweden

    5 h-index

    16 publications

    2.6K citations

  2. Institute of Chemical Technology

    Mumbai, India

    4 h-index

    9 publications

    317 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    10 publications

    317 citations

  4. Humboldt-Universität zu Berlin

    Berlin, Germany

    3 h-index

    7 publications

    254 citations

  5. Universidad Autónoma de Madrid

    Madrid, Spain

    3 h-index

    11 publications

    397 citations

  6. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    3 publications

    76 citations

  7. University of Pittsburgh

    Pittsburgh, United States

    2 h-index

    4 publications

    116 citations

  8. Fraunhofer Institute for Interfacial Engineering and Biotechnology

    Stuttgart, Germany

    2 h-index

    5 publications

    265 citations

1–8 of 160

Venues

  1. Biotechnology and Bioengineering

    5 publications · 209 citations

    5

    h-index

  2. Bioresource Technology

    4 publications · 253 citations

    4

    h-index

  3. Chemical Engineering Journal

    4 publications · 63 citations

    4

    h-index

  4. Enzyme and Microbial Technology

    3 publications · 110 citations

    3

    h-index

  5. Biocatalysis and Biotransformation

    3 publications · 62 citations

    3

    h-index

1–5