Concepedia

Enzyme Induction Interactions

Enzyme Induction Interactions is a pharmacodynamic drug interaction characterized by the increased metabolic activity of drug-metabolizing enzymes due to the upregulation of enzyme synthesis, leading to enhanced clearance and reduced efficacy of coadministered drugs.

35

Publications

2.1K

Citations

109

Authors

45

Institutions

Publications per year

2017–2026

0

Parents

Publications

35

Methoxyflurane nephrotoxicity. A study of dose response in man

M. J. Cousins · JAMA · 1973 · 288 citations

, , +17

A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.

Emilio Perucca, A Hedges, KA Makki et al. · British Journal of Clinical Pharmacology · 1984 · 190 citations · Full text

, , +13

The nifedipine-rifampin interaction. Evidence for induction of gut wall metabolism.

N Holtbecker, Martin F. Fromm, H. Kroemer et al. · Drug Metabolism and Disposition · 1996 · 179 citations

, , +17

Conversion of Daidzein and Genistein by an Anaerobic Bacterium Newly Isolated from the Mouse Intestine

Anastasia Matthies, Thomas Clavel, Michael Gütschow et al. · Applied and Environmental Microbiology · 2008 · 138 citations

, , +12

Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Effects on enzyme induction and immunotoxicity

Roy Bannister, D. Davis, Timothy R. Zacharewski et al. · Toxicology · 1987 · 120 citations

, , +9

1–5 of 35

Authors

109

  1. EP
    Emilio Perucca

    University of Pavia, Italy

    3 publications · 298 citations

    3

    h-index

  2. HU
    Haruto Uchino

    Kyoto University, Japan

    3 publications · 105 citations

    3

    h-index

  3. KI
    Kazuhiko Ito

    New York University, United States

    3 publications · 105 citations

    3

    h-index

  4. RH
    René H. Levy

    University of Washington, United States

    3 publications · 197 citations

    3

    h-index

  5. AA
    Allen A. Lai

    University of Washington, United States

    2 publications · 120 citations

    2

    h-index

1–5 of 109

Institutions

45

  1. University of Washington

    Seattle, United States

    3 h-index

    6 publications

    424 citations

  2. Hiroshima University

    Hiroshima, Japan

    3 h-index

    6 publications

    210 citations

  3. St Bartholomew's Hospital

    London, United Kingdom

    2 h-index

    2 publications

    221 citations

  4. University of Guelph

    Guelph, Canada

    2 h-index

    9 publications

    598 citations

  5. Neurological Surgery

    Rockville Centre, United States

    1 h-index

    2 publications

    26 citations

  6. Cornell University

    Ithaca, United States

    1 h-index

    3 publications

    36 citations

  7. Urology Foundation

    London, United Kingdom

    1 h-index

    1 publications

    77 citations

  8. The Graduate Center, CUNY

    New York, United States

    1 h-index

    7 publications

    84 citations

1–8 of 45

Venues

  1. JAMA

    4 publications · 448 citations

    4

    h-index

  2. Journal of Biological Chemistry

    JBC · 3 publications · 105 citations

    3

    h-index

  3. British Journal of Clinical Pharmacology

    BJCP · 3 publications · 294 citations

    3

    h-index

  4. Environmental Health Perspectives

    EHP · 2 publications · 30 citations

    2

    h-index

  5. Journal of Bacteriology

    JB · 1 publications · 77 citations

    1

    h-index

1–5