Concepedia

Enhancer Repression

Enhancer Repression is a regulatory mechanism in molecular genetics whereby specific proteins or non-coding elements selectively inhibit the activity of enhancer sequences to suppress gene expression in a spatiotemporal or context-dependent manner.

222

Publications

16.5K

Citations

1.1K

Authors

348

Institutions

Publications per year

2017–2026

42

Parents

Publications

222

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Michael T. Lam, Han Cho, Hanna P. Lesch et al. · Nature · 2013 · 551 citations

, , +12

DNA position-specific repression of transcription by a Drosophila zinc finger protein.

Pamela Geyer, Victor G. Corces · Genes & Development · 1992 · 426 citations · Full text

, , +17

Position-effect protection and enhancer blocking by the chicken β-globin insulator are separable activities

Félix Recillas‐Targa, Michael J. Pikaart, Bonnie Burgess-Beusse et al. · Proceedings of the National Academy of Sciences · 2002 · 380 citations

, , +16

Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.

K Park, Michael L. Atchison · Proceedings of the National Academy of Sciences · 1991 · 363 citations

, , +15

Specific interaction between enhancer-containing molecules and cellular components

Hans R. Schöler · Cell · 1984 · 357 citations

, , +14

1–5 of 222

Authors

1.1K

  1. PG
    Pavel Georgiev

    Institute of Gene Biology, Russia

    6 publications · 237 citations

    6

    h-index

  2. DD
    Dale Dorsett

    Saint Louis University, United States

    5 publications · 379 citations

    5

    h-index

  3. VG
    Victor G. Corces

    Johns Hopkins University, United States

    4 publications · 608 citations

    4

    h-index

  4. PG
    Pamela Geyer

    University of Iowa, United States

    3 publications · 641 citations

    3

    h-index

  5. RH
    Richard H. Goodman

    Vollum Institute, United States

    3 publications · 741 citations

    3

    h-index

1–5 of 1.1K

Institutions

348

  1. Harvard University

    Cambridge, United States

    11 h-index

    69 publications

    5.3K citations

  2. University of Pennsylvania

    Philadelphia, United States

    10 h-index

    21 publications

    2.7K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    22 publications

    3.3K citations

  4. Heidelberg University

    Heidelberg, Germany

    6 h-index

    13 publications

    1.5K citations

  5. University of California San Diego

    San Diego, United States

    5 h-index

    20 publications

    6.6K citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    5 h-index

    12 publications

    1K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    24 publications

    869 citations

  8. Inserm

    Paris, France

    5 h-index

    32 publications

    1.7K citations

1–8 of 348

Venues

  1. Molecular and Cellular Biology

    MCB · 30 publications · 1.7K citations

    22

    h-index

  2. Journal of Biological Chemistry

    JBC · 19 publications · 900 citations

    17

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 16 publications · 1.9K citations

    16

    h-index

  4. Genes & Development

    13 publications · 1.6K citations

    13

    h-index

  5. Nucleic Acids Research

    11 publications · 553 citations

    11

    h-index

1–5