Concepedia

Enhancer Orientation Dependence

Enhancer Orientation Dependence is a genomic regulatory principle denoting the phenomenon whereby the transcriptional activity of an enhancer element is influenced by its directional alignment relative to the target promoter, thereby distinguishing it from orientation-independent regulatory elements in gene expression control.

13

Publications

574

Citations

62

Authors

28

Institutions

Publications per year

2017–2026

1

Parents

Publications

13

Orientation-dependent interaction between Drosophila insulators is a property of this class of regulatory elements

Olga Kyrchanova, Darya Chetverina, Oksana Maksimenko et al. · Nucleic Acids Research · 2008 · 105 citations · Full text

, , +17

Identification of clustered YY1 binding sites in imprinting control regions

Jeong‐Do Kim, Angela K. Hinz, Anne Bergmann et al. · Genome Research · 2006 · 91 citations · Full text

, , +16

Position Effects Are Influenced by the Orientation of a Transgene with Respect to Flanking Chromatin

Yongqing Feng, Matthew C. Lorincz, Steve Fiering et al. · Molecular and Cellular Biology · 2001 · 82 citations · Full text

, , +14

Orientation-dependent Influence of an Intergenic Enhancer on the Promoter Activity of the Divergently Transcribed Mouse Shsp/αB-crystallin andMkbp/HspB2 Genes

Shivalingappa K. Swamynathan, Joram Piatigorsky · Journal of Biological Chemistry · 2002 · 60 citations · Full text

, , +16

The Ig mutator is dependent on the presence, position, and orientation of the large intron enhancer

Juergen Bachl, Carina Olsson, Nishay Chitkara et al. · Proceedings of the National Academy of Sciences · 1998 · 50 citations · Full text

, , +17

1–5 of 13

Authors

62

  1. DJ
    Damien J. Downes

    University of Oxford, United Kingdom

    1 publications · 35 citations

    1

    h-index

  2. JO
    Julie O’Neal

    Washington University in St. Louis, United States

    1 publications · 28 citations

    1

    h-index

  3. YB
    Yavor Bozhilov

    University of Oxford, United Kingdom

    1 publications · 35 citations

    1

    h-index

  4. WY
    Wei Yuan

    South China University of Technology, China

    1 publications · 43 citations

    1

    h-index

  5. EO
    Emmanuel Olivier

    Albert Einstein College of Medicine, United States

    1 publications · 35 citations

    1

    h-index

1–5 of 62

Institutions

28

  1. Albert Einstein College of Medicine

    Bronx, United States

    2 h-index

    3 publications

    199 citations

  2. Scottish National Blood Transfusion Service

    Edinburgh, United Kingdom

    1 h-index

    1 publications

    35 citations

  3. South China University of Technology

    Guangzhou, China

    1 h-index

    5 publications

    215 citations

  4. University of Glasgow

    Glasgow, United Kingdom

    1 h-index

    1 publications

    35 citations

  5. University of Tsukuba

    Tsukuba, Japan

    1 h-index

    4 publications

    52 citations

  6. Hiroshima University

    Hiroshima, Japan

    1 h-index

    2 publications

    26 citations

  7. MRC Weatherall Institute of Molecular Medicine

    Oxford, United Kingdom

    1 h-index

    6 publications

    210 citations

  8. National Institutes of Health

    Bethesda, United States

    1 h-index

    2 publications

    120 citations

1–8 of 28

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 70 citations

    2

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 73 citations

    2

    h-index

  3. Developmental Biology

    1 publications · 13 citations

    1

    h-index

  4. Gene

    1 publications · 15 citations

    1

    h-index

  5. Genome Research

    GR · 1 publications · 91 citations

    1

    h-index

1–5