Concepedia

Enhancer Modularity

Enhancer Modularity is a genomic organizational principle in which enhancer elements are composed of discrete, functionally separable units that can operate independently or in combination to regulate gene expression in a context-specific manner.

6

Publications

642

Citations

44

Authors

25

Institutions

Publications per year

2017–2026

1

Parents

Publications

6

Stepwise Modification of a Modular Enhancer Underlies Adaptation in a <i>Drosophila</i> Population

Mark Rebeiz, John E. Pool, Victoria A. Kassner et al. · Science · 2009 · 259 citations · Full text

, , +17

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

Catherine Fromental-Ramain, Masamoto Kanno, Hisayuki Nomiyama et al. · Cell · 1988 · 240 citations

, , +12

High level of novelty under the hood of convergent evolution

Steven M. Van Belleghem, Angelo Alberto Ruggieri, Carolina Concha et al. · Science · 2023 · 51 citations · Full text

, , +17

A SINE-Derived Element Constitutes a Unique Modular Enhancer for Mammalian Diencephalic Fgf8

Akiko Nakanishi, Naoki Kobayashi, Asuka Suzuki‐Hirano et al. · PLoS ONE · 2012 · 39 citations · Full text

, , +14

A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans

Hyun Cheol Roh, Ivan Dimitrov, Krupa Deshmukh et al. · Nucleic Acids Research · 2014 · 34 citations · Full text

, , +14

1–5 of 6

Authors

44

  1. JG
    James G. Ogilvie

    Auburn University, United States

    1 publications · 51 citations

    1

    h-index

  2. WO
    W. Owen McMillan

    Smithsonian Tropical Research Institute, Panama

    1 publications · 51 citations

    1

    h-index

  3. MK
    Masamoto Kanno

    Hiroshima University, Japan

    1 publications · 240 citations

    1

    h-index

  4. JE
    John E. Pool

    University of Wisconsin–Madison, United States

    1 publications · 259 citations

    1

    h-index

  5. TS
    Takeshi Sasaki

    Tokyo Institute of Technology, Japan

    1 publications · 39 citations

    1

    h-index

1–5 of 44

Institutions

25

  1. Cornell University

    Ithaca, United States

    2 h-index

    2 publications

    310 citations

  2. Kyoto University

    Kyoto, Japan

    2 h-index

    2 publications

    58 citations

  3. George Washington University

    Washington, United States

    1 h-index

    2 publications

    102 citations

  4. Washington University in St. Louis

    St Louis, United States

    1 h-index

    8 publications

    272 citations

  5. University of California, Berkeley

    Berkeley, United States

    1 h-index

    1 publications

    259 citations

  6. Auburn University

    Auburn, United States

    1 h-index

    2 publications

    102 citations

  7. University of California, Davis

    Davis, United States

    1 h-index

    1 publications

    259 citations

  8. University of Bayreuth

    Bayreuth, Germany

    1 h-index

    1 publications

    51 citations

1–8 of 25

Venues

  1. Science

    2 publications · 310 citations

    2

    h-index

  2. Cell

    1 publications · 240 citations

    1

    h-index

  3. PLoS ONE

    1 publications · 39 citations

    1

    h-index

  4. Nucleic Acids Research

    1 publications · 34 citations

    1

    h-index

  5. Fly

    1 publications · 19 citations

    1

    h-index

1–5