Concepedia

Enhancer Evolution

Enhancer Evolution is the evolutionary process by which noncoding regulatory DNA sequences that modulate gene expression in a spatiotemporal manner acquire mutations, leading to changes in enhancer activity, specificity, or function over phylogenetic time.

132

Publications

10.6K

Citations

607

Authors

258

Institutions

Publications per year

2017–2026

35

Parents

Publications

132

Enhancer Evolution across 20 Mammalian Species

Diego Villar, Camille Berthelot, Sarah Aldridge et al. · Cell · 2015 · 957 citations · Full text

, , +17

Interleukin-6–dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

Dennis Löffler, Katja Brocke-Heidrich, Gabriele Pfeifer et al. · Blood · 2007 · 635 citations · Full text

, , +13

Transcriptional Enhancers in Animal Development and Evolution

Current Biology · 2010 · 493 citations · Full text

, , +13

Shadow Enhancers as a Source of Evolutionary Novelty

Joung‐Woo Hong, David A. Hendrix, Michael Levine · Science · 2008 · 493 citations · Full text

, , +12

Human-Specific Gain of Function in a Developmental Enhancer

Shyam Prabhakar, Axel Visel, Jennifer A. Akiyama et al. · Science · 2008 · 390 citations · Full text

, , +14

1–5 of 132

Authors

607

  1. JC
    Justin Crocker

    Janelia Research Campus, United States

    5 publications · 234 citations

    5

    h-index

  2. AE
    Albert Erives

    University of Iowa, United States

    5 publications · 290 citations

    5

    h-index

  3. ML
    Michael Ludwig

    University of Bonn, Germany

    4 publications · 654 citations

    4

    h-index

  4. MR
    Mark Rebeiz

    University of Pittsburgh, United States

    4 publications · 434 citations

    4

    h-index

  5. MK
    Martin Kreitman

    University of Chicago, United States

    4 publications · 654 citations

    4

    h-index

1–5 of 607

Institutions

258

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    23 publications

    2.8K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    31 publications

    1.1K citations

  3. Lawrence Berkeley National Laboratory

    Berkeley, United States

    7 h-index

    45 publications

    11.6K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    23 publications

    6.9K citations

  5. University of Chicago

    Chicago, United States

    6 h-index

    17 publications

    1.8K citations

  6. University of California, Berkeley

    Berkeley, United States

    6 h-index

    10 publications

    1.5K citations

  7. University of Pittsburgh

    Pittsburgh, United States

    5 h-index

    13 publications

    1.5K citations

  8. Joint Genome Institute

    Berkeley, United States

    5 h-index

    25 publications

    6.4K citations

1–8 of 258

Venues

  1. Molecular Biology and Evolution

    MBE · 16 publications · 617 citations

    14

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 933 citations

    10

    h-index

  3. Journal of Virology

    JVI · 7 publications · 231 citations

    7

    h-index

  4. PLoS Genetics

    6 publications · 256 citations

    6

    h-index

  5. Genome Biology and Evolution

    GBE · 5 publications · 134 citations

    5

    h-index

1–5