Enhancer Evolution across 20 Mammalian Species

Diego Villar, Camille Berthelot, Sarah Aldridge, +12

Cell

Universal DNA methylation age across mammalian tissues

Ake T. Lu, Zhe Fei, Amin Haghani, +184

Nature Aging

Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1

Nuria Pescador, Diego Villar, Daniel Cifuentes, +10

PLoS ONE

Identification of a functional hypoxia-responsive element that regulates the expression of the <i>egl nine</i> homologue 3 (<i>egln3/phd3</i>) gene

Nuria Pescador, Yolanda Cuevas, Salvador Naranjo, +4

Biochemical Journal

Egln ExpressionTranscriptional RegulationDevelopmental BiologyRedox RegulatorMedicine +12

Complexity and conservation of regulatory landscapes underlie evolutionary resilience of mammalian gene expression

Camille Berthelot, Diego Villar, Julie E. Horvath, +2

Nature Ecology & Evolution

Natural SciencesGeneticsEvolutionary BiologyGene RegulationRegulatory Network Modelling +8

Universal DNA methylation age across mammalian tissues

Aimei Lu, Zhe Fei, Amin Haghani, +184

AgingEpigenetic ChangeGeneticsDna MethylationMolecular Genetics +14

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States

Konrad L M Rudolph, Bianca M. Schmitt, Diego Villar, +4

PLoS Genetics

GeneticsMolecular BiologyProtein SynthesisCodon UsageLong Non-coding Rna +14

LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions

Maša Roller, Ericca Stamper, Diego Villar, +7

Genome biology

Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate

Anna J. Jasinska, Ivette Zelaya, Susan K. Service, +32

Nature Genetics

Developmental BiologyGeneticsGenetic MechanismGenetic VariationPrimate Behavior +5

Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease

José R. Naranjo, Hongyu Zhang, Diego Villar, +16

Journal of Clinical Investigation

GeneticsNeurochemical BiomarkersSynaptic SignalingSocial SciencesNeurology +16