Concepedia

Enhancer Dynamics

Enhancer Dynamics is a regulatory phenomenon characterized by the temporally and spatially coordinated changes in the activity states of enhancer elements during developmental processes, distinguishing it from static or constitutive regulatory mechanisms by its dynamic responsiveness to cellular and environmental cues.

32

Publications

2.2K

Citations

295

Authors

132

Institutions

Publications per year

2017–2026

20

Parents

Publications

32

Human-Chimpanzee Differences in a FZD8 Enhancer Alter Cell-Cycle Dynamics in the Developing Neocortex

J. Lomax Boyd, Stephanie L. Skove, Jeremy P. Rouanet et al. · Current Biology · 2015 · 304 citations · Full text

, , +16

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis

Binbin Lai, Ji‐Eun Lee, Younghoon Jang et al. · Nucleic Acids Research · 2017 · 187 citations · Full text

, , +17

Evolutionary dynamics of the enhancer region of even-skipped in Drosophila.

Michael Ludwig, Martin Kreitman · Molecular Biology and Evolution · 1995 · 135 citations · Full text

, , +16

Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response

Ido Goldstein, Songjoon Baek, Diego M. Presman et al. · Genome Research · 2016 · 128 citations · Full text

, , +17

Enhancer methylation dynamics contribute to cancer plasticity and patient mortality

Rachel E. Bell, Tamar Golan, Danna Sheinboim et al. · Genome Research · 2016 · 112 citations · Full text

, , +17

1–5 of 32

Authors

295

  1. JA
    Jennifer A. Mitchell

    University of Toronto, Canada

    3 publications · 47 citations

    3

    h-index

  2. HS
    Harukazu Suzuki

    RIKEN Center for Integrative Medical Sciences, Japan

    2 publications · 114 citations

    2

    h-index

  3. TT
    Tiegh Taylor

    University of Toronto, Canada

    2 publications · 27 citations

    2

    h-index

  4. CH
    Chung-Chau Hon

    RIKEN Center for Integrative Medical Sciences, Japan

    2 publications · 114 citations

    2

    h-index

  5. EA
    Erik Arner

    RIKEN Center for Integrative Medical Sciences, Japan

    2 publications · 114 citations

    2

    h-index

1–5 of 295

Institutions

132

  1. National Institutes of Health

    Bethesda, United States

    4 h-index

    35 publications

    3.5K citations

  2. Harvard University

    Cambridge, United States

    4 h-index

    14 publications

    1.3K citations

  3. University of Toronto

    Toronto, Canada

    3 h-index

    9 publications

    141 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    5 publications

    319 citations

  5. Princess Margaret Cancer Centre

    Toronto, Canada

    3 h-index

    4 publications

    154 citations

  6. Hebrew University of Jerusalem

    Jerusalem, Israel

    2 h-index

    6 publications

    121 citations

  7. University of Chicago

    Chicago, United States

    2 h-index

    3 publications

    161 citations

  8. Dana-Farber Cancer Institute

    Boston, United States

    2 h-index

    5 publications

    233 citations

1–8 of 132

Venues

  1. Nucleic Acids Research

    4 publications · 239 citations

    4

    h-index

  2. Nature Communications

    3 publications · 231 citations

    3

    h-index

  3. eLife

    3 publications · 185 citations

    3

    h-index

  4. Molecular Cell

    2 publications · 130 citations

    2

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 29 citations

    2

    h-index

1–5