Concepedia

Enhancer Clusters

Enhancer Clusters is a genomic regulatory element that consists of dense aggregations of distal enhancer sequences, distinguished by their spatial organization and cooperative activity in driving high-level, cell-type-specific gene expression during development and disease.

111

Publications

19.1K

Citations

930

Authors

352

Institutions

Publications per year

2017–2026

46

Parents

Publications

111

Coactivator condensation at super-enhancers links phase separation and gene control

Benjamin R. Sabari, Alessandra Dall’Agnese, Ann Boija et al. · Science · 2018 · 2.7K citations

, , +17

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Won‐Ki Cho, Jan-Hendrik Spille, Micca Hecht et al. · Science · 2018 · 1.5K citations · Full text

, , +17

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

Julian Banerji, Laura Olson, Walter Schaffner · Cell · 1983 · 1.5K citations

, , +14

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

Anne Ephrussi, George M. Church, Susumu Tonegawa et al. · Science · 1985 · 860 citations

, , +17

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

Alexandre Melnikov, Anand Murugan, Xiaolan Zhang et al. · Nature Biotechnology · 2012 · 776 citations

, , +12

1–5 of 111

Authors

930

  1. WD
    Wouter de Laat

    University Medical Center Utrecht, Netherlands

    4 publications · 284 citations

    4

    h-index

  2. JF
    Jorge Ferrer

    Imperial College London, United Kingdom

    4 publications · 723 citations

    4

    h-index

  3. IM
    Irene Miguel-Escalada

    Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas, Spain

    3 publications · 592 citations

    3

    h-index

  4. LP
    Lorenzo Pasquali

    Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas, Spain

    3 publications · 605 citations

    3

    h-index

  5. BK
    Barbara K. Birshtein

    Albert Einstein College of Medicine, United States

    3 publications · 149 citations

    3

    h-index

1–5 of 930

Institutions

352

  1. National Institutes of Health

    Bethesda, United States

    10 h-index

    43 publications

    5.4K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    8 h-index

    26 publications

    32.2K citations

  3. Imperial College London

    London, United Kingdom

    6 h-index

    33 publications

    4.9K citations

  4. Inserm

    Paris, France

    6 h-index

    20 publications

    1.7K citations

  5. Harvard University

    Cambridge, United States

    5 h-index

    20 publications

    5.7K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    17 publications

    5K citations

  7. Yale University

    New Haven, United States

    5 h-index

    22 publications

    2.1K citations

  8. University of California, San Francisco

    San Francisco, United States

    5 h-index

    14 publications

    4.3K citations

1–8 of 352

Venues

  1. Nature Genetics

    8 publications · 2.1K citations

    8

    h-index

  2. Nucleic Acids Research

    8 publications · 730 citations

    8

    h-index

  3. Journal of Biological Chemistry

    JBC · 8 publications · 641 citations

    8

    h-index

  4. Nature Communications

    8 publications · 521 citations

    8

    h-index

  5. Cell

    4 publications · 2.3K citations

    4

    h-index

1–5