Concepedia

Enhancer Clustering

Enhancer Clustering is a genomic organization principle that refers to the spatial aggregation of multiple enhancer elements into discrete regulatory hubs, distinguished by their cooperative interaction to coordinately regulate target gene expression.

25

Publications

2.5K

Citations

188

Authors

88

Institutions

Publications per year

2017–2026

11

Parents

Publications

25

A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

Carsten Bahr, Lisa von Paleske, Veli Vural Uslu et al. · Nature · 2018 · 358 citations

, , +14

3D imaging of Sox2 enhancer clusters in embryonic stem cells

Zhe Liu, Wesley R. Legant, Bi‐Chang Chen et al. · eLife · 2014 · 281 citations · Full text

, , +17

Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments

Viraat Y. Goel, Miles K. Huseyin, Anders S. Hansen · Nature Genetics · 2023 · 248 citations · Full text

, , +14

Enhancer hubs and loop collisions identified from single-allele topologies

Amin Allahyar, Carlo Vermeulen, Britta A. M. Bouwman et al. · Nature Genetics · 2018 · 244 citations

, , +8

Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura

Benjamin P. Berman, Barret D. Pfeiffer, Todd Laverty et al. · Genome biology · 2004 · 216 citations · Full text

, , +17

1–5 of 25

Authors

188

  1. WD
    Wouter de Laat

    University Medical Center Utrecht, Netherlands

    4 publications · 461 citations

    4

    h-index

  2. MB
    Michael B. Eisen

    University of California, Berkeley, United States

    2 publications · 296 citations

    2

    h-index

  3. AS
    Anders S. Hansen

    Massachusetts Institute of Technology, United States

    2 publications · 287 citations

    2

    h-index

  4. GJ
    Guillaume J. Filion

    Centre for Genomic Regulation, Spain

    2 publications · 185 citations

    2

    h-index

  5. VY
    Viraat Y. Goel

    Massachusetts Institute of Technology, United States

    2 publications · 287 citations

    2

    h-index

1–5 of 188

Institutions

88

  1. University Medical Center Utrecht

    Utrecht, The Netherlands

    4 h-index

    33 publications

    4.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    12 publications

    2.9K citations

  3. Lawrence Berkeley National Laboratory

    Berkeley, United States

    4 h-index

    9 publications

    1.3K citations

  4. Hubrecht Institute for Developmental Biology and Stem Cell Research

    Utrecht, Netherlands

    3 h-index

    18 publications

    1.8K citations

  5. University of California, Berkeley

    Berkeley, United States

    3 h-index

    7 publications

    1.3K citations

  6. Oncode Institute

    Utrecht, Netherlands

    3 h-index

    17 publications

    3.2K citations

  7. German Cancer Research Center

    Heidelberg, Germany

    2 h-index

    10 publications

    2.6K citations

  8. National Center for Tumor Diseases

    Heidelberg, Germany

    2 h-index

    5 publications

    850 citations

1–8 of 88

Venues

  1. Nature Communications

    4 publications · 265 citations

    4

    h-index

  2. Nature Genetics

    3 publications · 629 citations

    3

    h-index

  3. Genome Research

    GR · 2 publications · 234 citations

    2

    h-index

  4. 1

    h-index

  5. PLoS ONE

    1 publications · 10 citations

    1

    h-index

1–5