Concepedia

Endolysosomal Degradation Avoidance

Endolysosomal Degradation Avoidance is a strategic mechanism in intracellular delivery systems that enables therapeutic agents to circumvent degradation within the endolysosomal pathway by preventing or escaping fusion with lysosomes, thereby ensuring cargo bioavailability in the cytoplasm.

10

Publications

664

Citations

75

Authors

32

Institutions

Publications per year

2017–2026

7

Parents

Publications

10

The importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailability

Archibald Paillard, François Hindré, C. Vignes‐Colombeix et al. · Biomaterials · 2010 · 143 citations

, , +16

Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system

James B. Delehanty, Christopher Bradburne, Kelly Boeneman et al. · Integrative Biology · 2010 · 128 citations

, , +9

Phenylboronic Acid Modification Augments the Lysosome Escape and Antitumor Efficacy of a Cylindrical Polymer Brush-Based Prodrug

Ruonan Wang, Changfeng Yin, Changren Liu et al. · Journal of the American Chemical Society · 2021 · 127 citations

, , +17

Tuning the Endocytosis Mechanism of Zr-Based Metal–Organic Frameworks through Linker Functionalization

Claudia Orellana‐Tavra, Salame Haddad, Ross J. Marshall et al. · ACS Applied Materials & Interfaces · 2017 · 65 citations · Full text

, , +17

Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells

Freya Joris, Lynn De Backer, Thijs Van de Vyver et al. · Journal of Controlled Release · 2017 · 58 citations · Full text

, , +14

1–5 of 10

Authors

75

  1. JB
    Juan B. Blanco‐Canosa

    Scripps Research Institute, United States

    1 publications · 128 citations

    1

    h-index

  2. TY
    Teerapong Yata

    Chulalongkorn University, Thailand

    1 publications · 44 citations

    1

    h-index

  3. EG
    Emmanuel Garcion

    Inserm, France

    1 publications · 143 citations

    1

    h-index

  4. UR
    Uta Reibetanz

    Leipzig University, Germany

    1 publications · 15 citations

    1

    h-index

  5. SW
    Sajee Waramit

    Imperial College London, United Kingdom

    1 publications · 44 citations

    1

    h-index

1–5 of 75

Institutions

32

  1. Rutgers Cancer Institute

    New Brunswick, United States

    1 h-index

    3 publications

    132 citations

  2. Luye Pharma (China)

    Shanghai, China

    1 h-index

    1 publications

    12 citations

  3. Imperial College London

    London, United Kingdom

    1 h-index

    9 publications

    396 citations

  4. Chiang Mai University

    Chiang Mai, Thailand

    1 h-index

    2 publications

    88 citations

  5. Nanjing University

    Nanjing, China

    1 h-index

    9 publications

    1.1K citations

  6. Nantes Université

    Nantes, France

    1 h-index

    1 publications

    143 citations

  7. Optical Sciences (United States)

    Huntsville, United States

    1 h-index

    4 publications

    512 citations

  8. UCLouvain

    Louvain-la-Neuve, Belgium

    1 h-index

    1 publications

    58 citations

1–8 of 32

Venues

  1. Biomaterials

    2 publications · 163 citations

    2

    h-index

  2. ACS Applied Materials & Interfaces

    1 publications · 65 citations

    1

    h-index

  3. Journal of the American Chemical Society

    JACS · 1 publications · 127 citations

    1

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 44 citations

    1

    h-index

  5. Journal of Materials Chemistry B

    1 publications · 15 citations

    1

    h-index

1–5