Concepedia

Empty Capsid Separation

Empty Capsid Separation is a purification method in virology and biopharmaceutical processing that specifically isolates intact viral capsids lacking genomic material from gene-filled capsids or other viral contaminants through physicochemical or chromatographic differentiation.

15

Publications

533

Citations

94

Authors

23

Institutions

Publications per year

2017–2026

10

Parents

Publications

15

A genetically engineered cell line that produces empty capsids of B19 (human) parvovirus.

Sachiko Kajigaya, Takashi Shimada, Shigeru Fujita et al. · Proceedings of the National Academy of Sciences · 1989 · 99 citations · Full text

, , +17

Empty Capsids in Column-Purified Recombinant Adenovirus Preparations

Gary Vellekamp, Frederick Porter, Suganto Sutjipto et al. · Human Gene Therapy · 2001 · 75 citations

, , +17

Anion-exchange HPLC assay for separation and quantification of empty and full capsids in multiple adeno-associated virus serotypes

Santoshkumar Khatwani, Ànna Pavlova, Zhu Pirot · Molecular Therapy — Methods & Clinical Development · 2021 · 70 citations · Full text

, , +11

Removal of empty capsids from adeno-associated virus preparations by multimodal metal affinity chromatography

Pete Gagnon, Maja Leskovec, Sara Drmota Prebil et al. · Journal of Chromatography A · 2021 · 39 citations · Full text

, , +16

Novel anion exchange membrane chromatography method for the separation of empty and full adeno‐associated virus

Adam Hejmowski, Kurt Boenning, J. Huato et al. · Biotechnology Journal · 2021 · 39 citations · Full text

, , +17

1–5 of 15

Authors

94

  1. SS
    Summer Swango

    CTI BioPharma (Italy), Italy

    1 publications · 21 citations

    1

    h-index

  2. MV
    Marcio Voloch

    Purdue University West Lafayette, United States

    1 publications · 75 citations

    1

    h-index

  3. BD
    Bieke Dejaegher

    Vrije Universiteit Brussel, Belgium

    1 publications · 18 citations

    1

    h-index

  4. AT
    Alexander Tracy

    University of Oxford, United Kingdom

    1 publications · 21 citations

    1

    h-index

  5. MD
    Michael D. Guerrero

    The University of Texas Rio Grande Valley, United States

    1 publications · 21 citations

    1

    h-index

1–5 of 94

Institutions

23

  1. Bristol-Myers Squibb (United States)

    New York, United States

    2 h-index

    5 publications

    147 citations

  2. Integrated BioTherapeutics (United States)

    Gaithersburg, United States

    1 h-index

    1 publications

    21 citations

  3. National Research Council Canada

    Ottawa, Canada

    1 h-index

    1 publications

    18 citations

  4. Ultragenyx Pharmaceutical (United States)

    Novato, United States

    1 h-index

    6 publications

    114 citations

  5. Lemuel Shattuck Hospital

    Jamaica Plain, United States

    1 h-index

    2 publications

    42 citations

  6. Spark Therapeutics (United States)

    Philadelphia, United States

    1 h-index

    3 publications

    96 citations

  7. Pall Corporation (United States)

    Port Washington, United States

    1 h-index

    5 publications

    195 citations

  8. Bristol-Myers Squibb (Germany)

    Munich, Germany

    1 h-index

    4 publications

    72 citations

1–8 of 23

Venues

  1. Biotechnology and Bioengineering

    2 publications · 39 citations

    2

    h-index

  2. Human Gene Therapy

    2 publications · 93 citations

    2

    h-index

  3. Journal of Chromatography A

    2 publications · 64 citations

    2

    h-index

  4. Biotechnology Journal

    3 publications · 72 citations

    2

    h-index

  5. 2

    h-index

1–5