Concepedia

Embryonic Closure Defects

Embryonic Closure Defects is a developmental anomaly characterized by the failure of proper fusion of embryonic tissue folds during morphogenesis, particularly in the neural tube or body wall, resulting in structural congenital malformations.

69

Publications

3.5K

Citations

229

Authors

125

Institutions

Publications per year

2017–2026

6

Parents

Publications

69

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin

Anton Roebroek, Lieve Umans, Ilse G.L. Pauli et al. · Development · 1998 · 302 citations · Full text

, , +17

A role for MEK kinase 1 in TGF‐β/activin‐induced epithelium movement and embryonic eyelid closure

Lin Zhang · The EMBO Journal · 2003 · 182 citations · Full text

, , +14

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes

Huimin Yu, Xin Ye, Nini Guo et al. · Development · 2012 · 154 citations · Full text

, , +17

Folic acid prevents exencephaly in Cited2 deficient mice

Juan Pedro Martı́nez-Barberá · Human Molecular Genetics · 2002 · 153 citations

, , +17

Biomechanical coupling facilitates spinal neural tube closure in mouse embryos

Gabriel L. Galea, Young-June Cho, Gauden Galea et al. · Proceedings of the National Academy of Sciences · 2017 · 123 citations · Full text

, , +17

1–5 of 69

Authors

229

  1. AJ
    Andrew J. Copp

    University College London, United Kingdom

    9 publications · 574 citations

    9

    h-index

  2. MJ
    M. J. Harris

    University of British Columbia, Canada

    4 publications · 236 citations

    4

    h-index

  3. DM
    D. M. Juriloff

    University of British Columbia, Canada

    4 publications · 236 citations

    4

    h-index

  4. RG
    Robert G. Nagele

    Rowan University, United States

    3 publications · 55 citations

    3

    h-index

  5. ND
    Nicholas D. E. Greene

    University College London, United Kingdom

    3 publications · 186 citations

    3

    h-index

1–5 of 229

Institutions

125

  1. Guy's Hospital

    London, United Kingdom

    5 h-index

    7 publications

    399 citations

  2. University College London

    London, United Kingdom

    5 h-index

    24 publications

    1.8K citations

  3. University of British Columbia

    Vancouver, Canada

    4 h-index

    14 publications

    833 citations

  4. Rutgers, The State University of New Jersey

    New Brunswick, United States

    3 h-index

    10 publications

    190 citations

  5. Maastricht University

    Maastricht, The Netherlands

    3 h-index

    6 publications

    283 citations

  6. Harvard University

    Cambridge, United States

    3 h-index

    6 publications

    766 citations

  7. University of London

    London, United Kingdom

    3 h-index

    4 publications

    259 citations

  8. KU Leuven

    Leuven, Belgium

    2 h-index

    12 publications

    2.1K citations

1–8 of 125

Venues

  1. Teratology

    12 publications · 449 citations

    11

    h-index

  2. Development

    8 publications · 728 citations

    8

    h-index

  3. American Journal of Medical Genetics

    4 publications · 130 citations

    4

    h-index

  4. Developmental Biology

    3 publications · 77 citations

    3

    h-index

  5. Child s Nervous System

    2 publications · 44 citations

    2

    h-index

1–5