Concepedia

Efflux Pump Mutations

Efflux Pump Mutations is a genetic alteration in the coding or regulatory sequences of efflux pump genes that enhances or modifies the expression, activity, or substrate specificity of efflux transporters, thereby contributing to antimicrobial resistance.

480

Publications

29.7K

Citations

2.4K

Authors

764

Institutions

Publications per year

2017–2026

149

Parents

Publications

480

Genes <i>acrA</i> and <i>acrB</i> encode a stress‐induced efflux system of <i>Escherichia coli</i>

Dzwokai Ma, David N. Cook, Marie Alberti et al. · Molecular Microbiology · 1995 · 609 citations

, , +17

CopA: An <i>Escherichia coli</i> Cu(I)-translocating P-type ATPase

Christopher Rensing, Bin Fan, Rakesh Sharma et al. · Proceedings of the National Academy of Sciences · 2000 · 519 citations · Full text

, , +16

Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms.

Keith Poole · PubMed · 2001 · 450 citations

, , +17

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

Yasuyuki Honjo, Christine A. Hrycyna, W Y Medina-Pérez et al. · PubMed · 2001 · 429 citations

, , +14

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

Margaret‐Mary Ameyaw, Fernando Regateiro, Tao Li et al. · Pharmacogenetics · 2001 · 411 citations

, , +15

1–5 of 480

Authors

2.4K

  1. AC
    Axel Cloeckaert

    Infectiologie et santé publique, France

    9 publications · 1.1K citations

    9

    h-index

  2. JL
    José Luis Martínez

    Centro Nacional de Biotecnología, Spain

    8 publications · 407 citations

    9

    h-index

  3. WM
    William M. Shafer

    Emory University, United States

    8 publications · 707 citations

    8

    h-index

  4. LJ
    Laura J. V. Piddock

    University of Birmingham, United Kingdom

    8 publications · 665 citations

    8

    h-index

  5. JL
    Juan L. Ramos

    Estación Experimental del Zaidín, Spain

    8 publications · 801 citations

    8

    h-index

1–5 of 2.4K

Institutions

764

  1. Emory University

    Atlanta, United States

    11 h-index

    29 publications

    2K citations

  2. University of Birmingham

    Birmingham, United Kingdom

    11 h-index

    26 publications

    2.1K citations

  3. Infectiologie et santé publique

    Nouzilly, France

    9 h-index

    23 publications

    2.1K citations

  4. Centro Nacional de Biotecnología

    Madrid, Spain

    9 h-index

    25 publications

    1.3K citations

  5. Inserm

    Paris, France

    8 h-index

    26 publications

    1.4K citations

  6. Uppsala University

    Uppsala, Sweden

    8 h-index

    28 publications

    1K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    8 h-index

    15 publications

    565 citations

  8. Harvard University

    Cambridge, United States

    8 h-index

    26 publications

    2.7K citations

1–8 of 764

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 87 publications · 7.6K citations

    51

    h-index

  2. Journal of Antimicrobial Chemotherapy

    JAC · 46 publications · 2.7K citations

    31

    h-index

  3. Journal of Bacteriology

    JB · 23 publications · 2.2K citations

    21

    h-index

  4. PLoS ONE

    18 publications · 1.1K citations

    18

    h-index

  5. Microbial Drug Resistance

    MDR · 16 publications · 870 citations

    14

    h-index

1–5