Concepedia

Efficacy Endpoints Validation

Efficacy Endpoints Validation is the systematic process of confirming that the selected measures or outcomes used to assess the effectiveness of an intervention in a clinical or experimental study accurately, reliably, and meaningfully reflect the intended therapeutic effect under investigation.

91

Publications

6.1K

Citations

804

Authors

544

Institutions

Publications per year

2017–2026

41

Parents

Publications

91

The validation of surrogate endpoints in meta-analyses of randomized experiments

Marc Buyse, Geert Molenberghs, Tomasz Burzykowski et al. · Biostatistics · 2000 · 605 citations · Full text

, , +15

Nivolumab plus ipilimumab versus sunitinib for first-line treatment of advanced renal cell carcinoma: extended 4-year follow-up of the phase III CheckMate 214 trial

Laurence Albigès, Nizar M. Tannir, Mauricio Burotto et al. · ESMO Open · 2020 · 522 citations · Full text

, , +17

Criteria for the Validation of Surrogate Endpoints in Randomized Experiments

Marc Buyse, Geert Molenberghs · Biometrics · 1998 · 427 citations

, , +12

Cryoballoon or radiofrequency ablation for symptomatic paroxysmal atrial fibrillation: reintervention, rehospitalization, and quality-of-life outcomes in the FIRE AND ICE trial

Karl-Heinz Kuck, Alexander Fürnkranz, K. R. Julian Chun et al. · European Heart Journal · 2016 · 348 citations · Full text

, , +13

Validation of Surrogate end Points in Multiple Randomized Clinical Trials with Failure Time end Points

Tomasz Burzykowski, Geert Molenberghs, Marc Buyse et al. · Journal of the Royal Statistical Society Series C (Applied Statistics) · 2001 · 218 citations · Full text

, , +14

1–5 of 91

Authors

804

  1. MB
    Marc Buyse

    International Drug Development Institute (Belgium), Belgium

    5 publications · 1.5K citations

    5

    h-index

  2. TB
    Tomasz Burzykowski

    Hasselt University, Belgium

    3 publications · 1K citations

    3

    h-index

  3. JS
    Joachim Sieper

    Charité - Universitätsmedizin Berlin, Germany

    3 publications · 85 citations

    3

    h-index

  4. GM
    Geert Molenberghs

    Hasselt University, Belgium

    3 publications · 1.3K citations

    3

    h-index

  5. MS
    Mark S. Freedman

    Ottawa Hospital, Canada

    2 publications · 87 citations

    2

    h-index

1–5 of 804

Institutions

544

  1. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    6 h-index

    7 publications

    214 citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    6 h-index

    7 publications

    1K citations

  3. National Cancer Institute

    Bethesda, United States

    5 h-index

    5 publications

    429 citations

  4. Queen Mary University of London

    London, United Kingdom

    4 h-index

    4 publications

    718 citations

  5. University of Ottawa

    Ottawa, Canada

    4 h-index

    4 publications

    234 citations

  6. Oregon Health & Science University

    Portland, United States

    4 h-index

    6 publications

    540 citations

  7. Washington University in St. Louis

    St Louis, United States

    4 h-index

    4 publications

    174 citations

  8. Université Paris Cité

    Paris, France

    4 h-index

    4 publications

    125 citations

1–8 of 544

Venues

  1. BioDrugs

    3 publications · 98 citations

    3

    h-index

  2. Annals of Oncology

    3 publications · 174 citations

    3

    h-index

  3. Annals of the Rheumatic Diseases

    ARD · 3 publications · 59 citations

    3

    h-index

  4. Statistics in Medicine

    2 publications · 138 citations

    2

    h-index

  5. Journal of Clinical Oncology

    2 publications · 133 citations

    2

    h-index

1–5