Concepedia

E/i Imbalance

E/I Imbalance is a neurological construct representing a deviation from the homeostatic equilibrium between excitatory and inhibitory synaptic activities in neural circuits, characterized by a disproportionate dominance of excitation over inhibition or vice versa.

35

Publications

2.6K

Citations

301

Authors

142

Institutions

Publications per year

2017–2026

28

Variants

Excitatory-inhibitory Imbalance

Parents

Publications

35

Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia

Colin Kehrer · Frontiers in Molecular Neuroscience · 2008 · 300 citations · Full text

, , +17

GABAergic dysfunction in excitatory and inhibitory (E/I) imbalance drives the pathogenesis of Alzheimer's disease

Danlei Bi, Lang Wen, Zujun Wu et al. · Alzheimer s & Dementia · 2020 · 242 citations

, , +17

Measurement of excitation-inhibition ratio in autism spectrum disorder using critical brain dynamics

Hilgo Bruining, Richard Hardstone, Erika L. Juárez-Martinez et al. · Scientific Reports · 2020 · 226 citations · Full text

, , +17

Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

Stavros Trakoshis, Pablo Martínez‐Cañada, Federico Rocchi et al. · eLife · 2020 · 187 citations · Full text

, , +17

E-I balance and human diseases – from molecules to networking

Sabrina A. Eichler · Frontiers in Molecular Neuroscience · 2008 · 179 citations · Full text

, , +17

1–5 of 35

Authors

301

  1. KL
    Klaus Linkenkaer‐Hansen

    Amsterdam Neuroscience, Netherlands

    3 publications · 349 citations

    3

    h-index

  2. JE
    Jaime E. C. Hallak

    Universidade de São Paulo, Brazil

    2 publications · 140 citations

    2

    h-index

  3. AG
    Alessandro Gozzi

    Italian Institute of Technology, Italy

    2 publications · 199 citations

    2

    h-index

  4. WY
    Wonsang You

    Children's National, United States

    2 publications · 199 citations

    2

    h-index

  5. MM
    Marija Markicevic

    ETH Zurich, Switzerland

    2 publications · 199 citations

    2

    h-index

1–5 of 301

Institutions

142

  1. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    15 publications

    1.4K citations

  2. New York University

    New York, United States

    3 h-index

    3 publications

    366 citations

  3. Amsterdam University Medical Centers

    Amsterdam, The Netherlands

    3 h-index

    16 publications

    1.1K citations

  4. University of Washington

    Seattle, United States

    3 h-index

    5 publications

    378 citations

  5. Amsterdam Neuroscience

    Amsterdam, The Netherlands

    3 h-index

    24 publications

    2.8K citations

  6. University of Toronto

    Toronto, Canada

    2 h-index

    2 publications

    199 citations

  7. SickKids Foundation

    Toronto, Canada

    2 h-index

    2 publications

    199 citations

  8. ETH Zurich

    Zurich, Switzerland

    2 h-index

    4 publications

    398 citations

1–8 of 142

Venues

  1. Frontiers in Molecular Neuroscience

    3 publications · 516 citations

    3

    h-index

  2. Nature Communications

    2 publications · 287 citations

    2

    h-index

  3. Schizophrenia Bulletin

    2 publications · 64 citations

    2

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 40 citations

    2

    h-index

  5. PLoS ONE

    2 publications · 61 citations

    2

    h-index

1–5