Concepedia

Drosophila Trithorax Function

Drosophila Trithorax Function is a molecular genetic mechanism in Drosophila melanogaster that maintains active transcription of homeotic genes through histone modification and chromatin remodeling, thereby ensuring proper developmental gene expression patterns.

64

Publications

8.8K

Citations

251

Authors

96

Institutions

Publications per year

2017–2026

1

Parents

Publications

64

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

Douglas Tkachuk, Sabine Köhler, Michael L. Cleary · Cell · 1992 · 932 citations

, , +16

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

Y Gu, Tatsuya Nakamura, Hansjüerg Alder et al. · Cell · 1992 · 834 citations

, , +13

Leukemia Proto-Oncoprotein MLL Forms a SET1-Like Histone Methyltransferase Complex with Menin To Regulate <i>Hox</i> Gene Expression

Akihiko Yokoyama, Zhong Wang, Joanna Wysocka et al. · Molecular and Cellular Biology · 2004 · 644 citations · Full text

, , +17

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

Deqing Hu, Xin Gao, Marc A. Morgan et al. · Molecular and Cellular Biology · 2013 · 433 citations · Full text

, , +17

The Trithorax-like gene encodes the Drosophila GAGA factor

Gabriella Farkas, János Gausz, Mireille Galloni et al. · Nature · 1994 · 422 citations

, , +5

1–5 of 64

Authors

251

  1. AS
    Allen Shearn

    Johns Hopkins University, United States

    6 publications · 806 citations

    6

    h-index

  2. EC
    Eli Canaani

    Weizmann Institute of Science, Israel

    5 publications · 1.4K citations

    5

    h-index

  3. TN
    Tatsuya Nakamura

    Weizmann Institute of Science, Israel

    5 publications · 1.6K citations

    5

    h-index

  4. PJ
    Peter J. Harte

    Case Western Reserve University, United States

    5 publications · 503 citations

    5

    h-index

  5. PW
    Philip W. Ingham

    University of Sheffield, United Kingdom

    5 publications · 432 citations

    5

    h-index

1–5 of 251

Institutions

96

  1. Johns Hopkins University

    Baltimore, United States

    5 h-index

    11 publications

    1K citations

  2. Case Western Reserve University

    Cleveland, United States

    5 h-index

    14 publications

    1.5K citations

  3. Sidney Kimmel Cancer Center

    Philadelphia, United States

    4 h-index

    29 publications

    3.8K citations

  4. Thomas Jefferson University

    Philadelphia, United States

    4 h-index

    18 publications

    7.5K citations

  5. Stanford University

    Stanford, United States

    4 h-index

    17 publications

    5.9K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    17 publications

    2.9K citations

  7. Weizmann Institute of Science

    Rehovot, Israel

    3 h-index

    14 publications

    2.6K citations

  8. Jefferson Institute

    Washington, United States

    3 h-index

    12 publications

    2.5K citations

1–8 of 96

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 973 citations

    9

    h-index

  2. Development

    8 publications · 856 citations

    8

    h-index

  3. Genetics

    6 publications · 399 citations

    6

    h-index

  4. Molecular and Cellular Biology

    MCB · 5 publications · 1.4K citations

    5

    h-index

  5. Mechanisms of Development

    MOD · 4 publications · 309 citations

    4

    h-index

1–5