Concepedia

Driver Mutation Diversity

Driver Mutation Diversity is a genomic heterogeneity metric that quantifies the variation in cancer-promoting genetic alterations across distinct tumors within a patient population, distinguished by its focus on the diversity of driver mutations rather than passenger mutations or overall mutational burden.

27

Publications

2.9K

Citations

399

Authors

132

Institutions

Publications per year

2017–2026

18

Parents

Publications

27

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

Yasushi Totoki, Kenji Tatsuno, Kyle R. Covington et al. · Nature Genetics · 2014 · 779 citations

, , +14

Translational Implications of Tumor Heterogeneity

Clinical Cancer Research · 2015 · 527 citations · Full text

, , +17

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

Alvin P. Makohon-Moore, Ming Zhang, Johannes G. Reiter et al. · Nature Genetics · 2017 · 419 citations · Full text

, , +17

The Path to Cancer — Three Strikes and You're Out

Bert Vogelstein, Kenneth W. Kinzler · New England Journal of Medicine · 2015 · 329 citations

, , +17

Genomic and Epigenomic Heterogeneity of Hepatocellular Carcinoma

De‐Chen Lin, Anand Mayakonda, Huy Q. Dinh et al. · Cancer Research · 2017 · 242 citations · Full text

, , +16

1–5 of 27

Authors

399

  1. KW
    Kenneth W. Kinzler

    Johns Hopkins University, United States

    2 publications · 748 citations

    2

    h-index

  2. BV
    Bert Vogelstein

    Johns Hopkins University, United States

    2 publications · 748 citations

    2

    h-index

  3. DF
    David Fabrizio

    Foundation Medicine (United States)

    1 publications · 28 citations

    1

    h-index

  4. AG
    Ann G. Schwartz

    The Barbara Ann Karmanos Cancer Institute, United States

    1 publications · 56 citations

    1

    h-index

  5. YZ
    Yiming Zhu

    Shanghai Ninth People's Hospital, China

    1 publications · 779 citations

    1

    h-index

1–5 of 399

Institutions

132

  1. Inserm

    Paris, France

    2 h-index

    15 publications

    381 citations

  2. University Hospital Heidelberg

    Heidelberg, Germany

    2 h-index

    22 publications

    501 citations

  3. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    2 h-index

    3 publications

    170 citations

  4. Johns Hopkins University

    Baltimore, United States

    2 h-index

    11 publications

    4.4K citations

  5. Heidelberg University

    Heidelberg, Germany

    2 h-index

    25 publications

    552 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    3 publications

    1.1K citations

  7. Hospital Universitario Central de Asturias

    Oviedo, Spain

    1 h-index

    2 publications

    212 citations

  8. Gunma University

    Maebashi, Japan

    1 h-index

    1 publications

    22 citations

1–8 of 132

Venues

  1. Nature Communications

    3 publications · 348 citations

    3

    h-index

  2. Lung Cancer

    2 publications · 72 citations

    2

    h-index

  3. Nature Genetics

    2 publications · 1.2K citations

    2

    h-index

  4. Human Pathology

    2 publications · 47 citations

    2

    h-index

  5. Journal of Thoracic Oncology

    2 publications · 200 citations

    2

    h-index

1–5