Concepedia

Dose-proportionality Metrics

Dose-Proportionality Metrics is a quantitative method used in pharmacokinetic analysis to assess the constancy of drug exposure relative to administered dose across different dose levels, distinguished by its specific application in determining whether systemic exposure increases in direct proportion to dose.

48

Publications

2K

Citations

265

Authors

102

Institutions

Publications per year

2017–2026

9

Parents

Publications

48

Confidence Interval Criteria for Assessment of Dose Proportionality

Brian P. Smith · Pharmaceutical Research · 2000 · 352 citations

, , +13

Assessment of Dose Proportionality: Report from the Statisticians in the Pharmaceutical Industry/Pharmacokinetics UK Joint Working Party

Kevin Gough, Michael G. Hutchison, Oliver N. Keene et al. · Drug Information Journal · 1995 · 266 citations

, , +12

Strong Relationship between Oral Dose and Tenofovir Hair Levels in a Randomized Trial: Hair as a Potential Adherence Measure for Pre-Exposure Prophylaxis (PrEP)

Albert Liu, Qiyun Yang, Yong Huang et al. · PLoS ONE · 2014 · 152 citations · Full text

, , +16

XP13512 [(±)-1-([(α-Isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane Acetic Acid], A Novel Gabapentin Prodrug: II. Improved Oral Bioavailability, Dose Proportionality, and Colonic Absorption Compared with Gabapentin in Rats and Monkeys

Kenneth C. Cundy, Thamil Annamalai, Lin Bu et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 122 citations

, , +17

A double-blind, randomized, incomplete crossover trial to assess the dose proportionality of rosuvastatin in healthy volunteers

Paul Martin, Mike J. Warwick, Aaron Dane et al. · Clinical Therapeutics · 2003 · 61 citations

, , +12

1–5 of 48

Authors

265

  1. MW
    Muhammad Wahajuddin

    Central Drug Research Institute, India

    2 publications · 20 citations

    2

    h-index

  2. WT
    William Tracewell

    Teva Pharmaceuticals (United States), United States

    2 publications · 43 citations

    2

    h-index

  3. TR
    Tianqi Rui

    Nanjing University of Chinese Medicine, China

    1 publications · 57 citations

    1

    h-index

  4. SR
    Steven R. Lentz

    University of Iowa, United States

    1 publications · 31 citations

    1

    h-index

  5. QY
    Qiyun Yang

    University of California, San Francisco, United States

    1 publications · 152 citations

    1

    h-index

1–5 of 265

Institutions

102

  1. Novartis (Switzerland)

    Basel, Switzerland

    3 h-index

    9 publications

    187 citations

  2. Research Triangle Park Foundation

    Durham, United States

    3 h-index

    4 publications

    88 citations

  3. United States Military Academy

    West Point, United States

    2 h-index

    6 publications

    144 citations

  4. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    2 h-index

    13 publications

    379 citations

  5. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    2 h-index

    12 publications

    308 citations

  6. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    2 h-index

    6 publications

    776 citations

  7. Eli Lilly (United States)

    Indianapolis, United States

    2 h-index

    3 publications

    735 citations

  8. Central Drug Research Institute

    Lucknow, India

    2 h-index

    14 publications

    140 citations

1–8 of 102

Venues

  1. The Journal of Clinical Pharmacology

    3 publications · 76 citations

    3

    h-index

  2. Clinical Drug Investigation

    3 publications · 46 citations

    3

    h-index

  3. European Journal of Clinical Pharmacology

    3 publications · 66 citations

    3

    h-index

  4. Journal of Child and Adolescent Psychopharmacology

    JCAP · 2 publications · 32 citations

    2

    h-index

  5. Cancer Chemotherapy and Pharmacology

    2 publications · 57 citations

    2

    h-index

1–5