Concepedia

Dose-dependent Extraction

Dose-Dependent Extraction is a pharmacokinetic phenomenon in which the extent of drug removal by the liver during the first pass varies as a function of the administered dose, typically due to saturation of hepatic metabolic enzymes or transport mechanisms.

87

Publications

3.2K

Citations

355

Authors

106

Institutions

Publications per year

2017–2026

17

Parents

Publications

87

The Disposition of Propranolol

David G. Shand, Robert E. Rangno · Pharmacology · 2008 · 233 citations

, , +17

The Disposition of Propranolol

David G. Shand, Robert E. Rangno, Gwyn H. Evans · Pharmacology · 2008 · 186 citations

, , +17

Adaptogenic and safety evaluation of seabuckthorn (Hippophae rhamnoides) leaf extract: A dose dependent study

Shalini Saggu, H. M. Divekar, Vanita Gupta et al. · Food and Chemical Toxicology · 2006 · 144 citations

, , +7

Pharmacokinetics and first-pass metabolism of astaxanthin in rats

Hye Duck Choi, Hee Eun Kang, Sihyung Yang et al. · British Journal Of Nutrition · 2010 · 107 citations · Full text

, , +17

Antiproliferation Effect and Apoptosis Mechanism of Prostate Cancer Cell PC-3 by Flavonoids and Saponins Prepared from<i>Gynostemma pentaphyllum</i>

Tse‐Chou Cheng, Jyh‐Feng Lu, Jinn‐Shyan Wang et al. · Journal of Agricultural and Food Chemistry · 2011 · 85 citations

, , +14

1–5 of 87

Authors

355

  1. DG
    David G. Shand

    Vanderbilt University, United States

    4 publications · 490 citations

    4

    h-index

  2. RE
    Robert E. Rangno

    Montreal General Hospital, Canada

    3 publications · 480 citations

    3

    h-index

  3. GH
    Gwyn H. Evans

    Vanderbilt University, United States

    2 publications · 243 citations

    2

    h-index

  4. AW
    Adisa W.A.

    1 publications · 11 citations

    1

    h-index

  5. AR
    Ann Roche

    Flinders University, Australia

    1 publications · 16 citations

    1

    h-index

1–5 of 355

Institutions

106

  1. Vanderbilt University

    Nashville, United States

    3 h-index

    7 publications

    1K citations

  2. Seoul National University

    Seoul, South Korea

    2 h-index

    9 publications

    755 citations

  3. Medical University of South Carolina

    Charleston, United States

    2 h-index

    5 publications

    219 citations

  4. University of California San Diego

    San Diego, United States

    2 h-index

    7 publications

    208 citations

  5. Vanderbilt University Medical Center

    Nashville, United States

    2 h-index

    4 publications

    838 citations

  6. Sorbonne Université

    Paris, France

    1 h-index

    1 publications

    30 citations

  7. Virginia Tech

    Blacksburg, United States

    1 h-index

    7 publications

    238 citations

  8. Szent János Kórház

    Budapest, Hungary

    1 h-index

    4 publications

    56 citations

1–8 of 106

Venues

  1. PubMed

    Repository · 8 publications · 361 citations

    8

    h-index

  2. Drug Metabolism and Disposition

    5 publications · 59 citations

    5

    h-index

  3. Endocrinology

    3 publications · 112 citations

    3

    h-index

  4. Journal of Medicinal Plants Research

    JMPR · 3 publications · 113 citations

    3

    h-index

  5. Phytotherapy Research

    PTR · 2 publications · 69 citations

    2

    h-index

1–5