Concepedia

Dose Response Genomics

Dose Response Genomics is a systematic framework within comparative pharmacogenetics that integrates genomic variability with quantitative dose-response relationships to identify genetic determinants influencing individual differences in drug response magnitude and therapeutic threshold.

9

Publications

407

Citations

92

Authors

49

Institutions

Publications per year

2017–2026

3

Parents

Publications

9

Genomic impact of transient low-dose decitabine treatment on primary AML cells

Jeffery M. Klco, David H. Spencer, Tamara Lamprecht et al. · Blood · 2013 · 204 citations

, , +15

'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans

Marlon J. Jetten, Stan Gaj, Ainhoa Ruiz‐Aracama et al. · Toxicology and Applied Pharmacology · 2012 · 48 citations

, , +12

A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT

Chad Brown, Tammy M. Havener, Marisa W. Medina et al. · Pharmacogenetics and Genomics · 2012 · 32 citations · Full text

, , +16

Gene interaction network analysis suggests differences between high and low doses of acetaminophen

Hiroyoshi Toyoshiba, Takeharu Yamanaka, Fred Parham et al. · Toxicology and Applied Pharmacology · 2006 · 26 citations

, , +10

Genetic Determinants of Warfarin Maintenance Dose and Time in Therapeutic Treatment Range: A RE-LY Genomics Substudy

Niclas Eriksson, Lars Wallentin, Lars Berglund et al. · Pharmacogenomics · 2016 · 25 citations · Full text

, , +14

1–5 of 9

Authors

92

  1. JL
    Jean Laplanche

    Inserm, France

    2 publications · 35 citations

    2

    h-index

  2. FV
    Florence Vorspan

    Inserm, France

    2 publications · 35 citations

    2

    h-index

  3. FB
    Frank Bellivier

    Inserm, France

    2 publications · 35 citations

    2

    h-index

  4. VB
    Vanessa Bloch

    Inserm, France

    2 publications · 35 citations

    2

    h-index

  5. SM
    Stéphane Mouly

    Hôpital Lariboisière, France

    2 publications · 35 citations

    2

    h-index

1–5 of 92

Institutions

49

  1. Assistance Publique – Hôpitaux de Paris

    Paris, France

    2 h-index

    8 publications

    133 citations

  2. Université Paris Cité

    Paris, France

    2 h-index

    18 publications

    308 citations

  3. Inserm

    Paris, France

    2 h-index

    17 publications

    287 citations

  4. Sorbonne Paris Cité

    Paris, France

    2 h-index

    18 publications

    308 citations

  5. Optimisation Thérapeutique en Neuropsychopharmacologie

    Paris, France

    2 h-index

    17 publications

    287 citations

  6. Hôpital Fernand-Widal

    Paris, France

    2 h-index

    7 publications

    119 citations

  7. North Carolina State University

    Raleigh, United States

    1 h-index

    2 publications

    64 citations

  8. Hamilton Health Sciences

    Hamilton, Canada

    1 h-index

    4 publications

    100 citations

1–8 of 49

Venues

  1. Pharmacogenomics

    2 publications · 41 citations

    2

    h-index

  2. Toxicology and Applied Pharmacology

    TAAP · 2 publications · 74 citations

    2

    h-index

  3. Fundamental and Clinical Pharmacology

    FCP · 1 publications · 14 citations

    1

    h-index

  4. 1

    h-index

  5. Blood

    1 publications · 204 citations

    1

    h-index

1–5