Concepedia

Dose Rate Optimization

Dose Rate Optimization is a methodological framework within infusion kinetics that systematically determines the optimal rate of drug administration to achieve desired therapeutic concentrations while minimizing toxicity and inter-patient variability.

52

Publications

2.2K

Citations

232

Authors

89

Institutions

Publications per year

2017–2026

14

Parents

Publications

52

Pharmacologically directed design of the dose rate and schedule of 2',2'-difluorodeoxycytidine (Gemcitabine) administration in leukemia.

Ralf Grunewald, Hagop M. Kantarjian, M Keating et al. · PubMed · 1990 · 210 citations

, , +17

Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion

Kimmo Porkka, H. Jean Khoury, Ronald Paquette et al. · Cancer · 2009 · 155 citations · Full text

, , +11

Paclitaxel in Breast Cancer

Edith A. Perez · The Oncologist · 1998 · 153 citations · Full text

, , +17

Simultaneous dose and dose rate optimization (SDDRO) for FLASH proton therapy

Hao Gao, Bo-Wen Lin, Yu-Ting Lin et al. · Medical Physics · 2020 · 104 citations

, , +17

A New Dose‐Finding Design for Bivariate Outcomes

Anastasia Ivanova · Biometrics · 2003 · 96 citations

, , +15

1–5 of 52

Authors

232

  1. HG
    Hao Gao

    Shanghai Jiao Tong University, China

    3 publications · 222 citations

    3

    h-index

  2. YL
    Yu-Ting Lin

    University of California, Irvine, United States

    3 publications · 222 citations

    3

    h-index

  3. DR
    Dan Ruan

    University of California, Los Angeles, United States

    2 publications · 35 citations

    2

    h-index

  4. HM
    Hagop M. Kantarjian

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 223 citations

    2

    h-index

  5. YM
    Yousif Matloub

    The University of Texas Southwestern Medical Center, United States

    2 publications · 168 citations

    2

    h-index

1–5 of 232

Institutions

89

  1. Emory University

    Atlanta, United States

    5 h-index

    14 publications

    1.2K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    4 h-index

    7 publications

    468 citations

  3. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    8 publications

    281 citations

  4. Bristol-Myers Squibb (United States)

    New York, United States

    3 h-index

    21 publications

    728 citations

  5. Washington University in St. Louis

    St Louis, United States

    2 h-index

    4 publications

    149 citations

  6. National Cancer Institute

    Bethesda, United States

    2 h-index

    2 publications

    44 citations

  7. Cornell University

    Ithaca, United States

    2 h-index

    2 publications

    61 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    3 publications

    204 citations

1–8 of 89

Venues

  1. 8

    h-index

  2. Medical Physics

    6 publications · 319 citations

    5

    h-index

  3. PubMed

    Repository · 4 publications · 284 citations

    4

    h-index

  4. Physics in Medicine and Biology

    4 publications · 105 citations

    4

    h-index

  5. Journal of Clinical Oncology

    3 publications · 105 citations

    3

    h-index

1–5