Concepedia

Dose Escalation Effects

Dose Escalation Effects is a pharmacological phenomenon characterized by changes in drug clearance that occur as a direct result of increasing the administered dose, typically reflecting nonlinear pharmacokinetics due to saturation of metabolic or elimination pathways.

46

Publications

3.2K

Citations

375

Authors

135

Institutions

Publications per year

2017–2026

8

Parents

Publications

46

The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients

Marie‐Catherine Vozenin, Pauline De Fornel, Kristoffer Petersson et al. · Clinical Cancer Research · 2018 · 748 citations

, , +14

Escalation of methamphetamine self-administration in rats: a dose–effect function

Osamu Kitamura, Sunmee Wee, Sheila E. Specio et al. · Psychopharmacology · 2006 · 219 citations

, , +14

BEACOPP, a new dose-escalated and accelerated regimen, is at least as effective as COPP/ABVD in patients with advanced-stage Hodgkin's lymphoma: interim report from a trial of the German Hodgkin's Lymphoma Study Group.

Volker Diehl, Jeremy Franklin, Dirk Hasenclever et al. · Journal of Clinical Oncology · 1998 · 196 citations

, , +15

Prolonged Correction of Serum Phosphorus in Adults With X-Linked Hypophosphatemia Using Monthly Doses of KRN23

Erik A. Imel, Xiaoping Zhang, Mary D. Ruppe et al. · The Journal of Clinical Endocrinology & Metabolism · 2015 · 169 citations · Full text

, , +17

Intrapatient Cetuximab Dose Escalation in Metastatic Colorectal Cancer According to the Grade of Early Skin Reactions: The Randomized EVEREST Study

Eric Van Cutsem, Sabine Tejpar, Dirk Vanbeckevoort et al. · Journal of Clinical Oncology · 2012 · 131 citations · Full text

, , +17

1–5 of 46

Authors

375

  1. MP
    Marc Peeters

    Antwerp University Hospital, Belgium

    3 publications · 245 citations

    3

    h-index

  2. ST
    Sabine Tejpar

    KU Leuven, Belgium

    3 publications · 245 citations

    3

    h-index

  3. EV
    Eric Van Cutsem

    KU Leuven, Belgium

    3 publications · 245 citations

    3

    h-index

  4. YH
    Yves Humblet

    UCLouvain, Belgium

    3 publications · 245 citations

    3

    h-index

  5. JS
    Jeffrey S. Humphrey

    Duke Medical Center, United States

    2 publications · 233 citations

    2

    h-index

1–5 of 375

Institutions

135

  1. Pfizer (United States)

    New York, United States

    3 h-index

    8 publications

    366 citations

  2. Yale University

    New Haven, United States

    2 h-index

    4 publications

    466 citations

  3. Methodist Hospital

    Sacramento, United States

    2 h-index

    2 publications

    233 citations

  4. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    2 h-index

    15 publications

    2.3K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    2 h-index

    2 publications

    91 citations

  6. Children's Hospital of Philadelphia

    Philadelphia, United States

    2 h-index

    13 publications

    1.4K citations

  7. Indiana University School of Medicine

    Indianapolis, United States

    2 h-index

    4 publications

    466 citations

  8. Shriners Hospitals for Children - Canada

    Montreal, Canada

    2 h-index

    2 publications

    233 citations

1–8 of 135

Venues

  1. Journal of Clinical Oncology

    8 publications · 566 citations

    8

    h-index

  2. PubMed

    Repository · 6 publications · 245 citations

    6

    h-index

  3. Clinical Cancer Research

    3 publications · 939 citations

    3

    h-index

  4. British Journal of Cancer

    BJC · 2 publications · 134 citations

    2

    h-index

  5. Cancer

    2 publications · 35 citations

    2

    h-index

1–5