Concepedia

Dose Addition Models

Dose Addition Models is a toxicological framework that assumes the combined effect of multiple chemicals occurs when their doses are additive, with each component contributing proportionally to the overall response as if they were different doses of the same compound.

26

Publications

894

Citations

119

Authors

50

Institutions

Publications per year

2017–2026

8

Parents

Publications

26

Deviation from Additivity with Estrogenic Mixtures Containing 4-Nonylphenol and 4<i>-tert</i>-Octylphenol Detected in the E-SCREEN Assay

Nissanka Rajapakse, Elisabete Silva, Martin Scholze et al. · Environmental Science & Technology · 2004 · 94 citations

, , +12

Generalized Concentration Addition Predicts Joint Effects of Aryl Hydrocarbon Receptor Agonists with Partial Agonists and Competitive Antagonists

Gregory J. Howard, Jennifer J. Schlezinger, Mark E. Hahn et al. · Environmental Health Perspectives · 2009 · 69 citations · Full text

, , +15

Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in Rats

Kembra L. Howdeshell, Cynthia V. Rider, Vickie S. Wilson et al. · Toxicological Sciences · 2015 · 67 citations · Full text

, , +17

Methodology for health risk assessment of combined exposures to multiple chemicals

Anna Beronius, Johanna Zilliacus, Annika Hanberg et al. · Food and Chemical Toxicology · 2020 · 59 citations · Full text

, , +15

Extending the Applicability of the Dose Addition Model to the Assessment of Chemical Mixtures of Partial Agonists by Using a Novel Toxic Unit Extrapolation Method

Martin Scholze, Elisabete Silva, Andreas Kortenkamp · PLoS ONE · 2014 · 55 citations · Full text

, , +14

1–5 of 26

Authors

119

  1. AK
    Andreas Kortenkamp

    Brunel University of London, United Kingdom

    3 publications · 162 citations

    3

    h-index

  2. MS
    Martin Scholze

    Brunel University of London, United Kingdom

    3 publications · 179 citations

    3

    h-index

  3. JM
    Julia Metzner

    Goethe University Frankfurt, Germany

    2 publications · 25 citations

    2

    h-index

  4. AP
    Alberto Protzel

    Environmental Protection Agency, United States

    2 publications · 49 citations

    2

    h-index

  5. GR
    Glenn Rice

    Environmental Protection Agency, United States

    2 publications · 49 citations

    2

    h-index

1–5 of 119

Institutions

50

  1. Environmental Protection Agency

    Washington, United States

    6 h-index

    21 publications

    730 citations

  2. Research Triangle Park Foundation

    Durham, United States

    3 h-index

    12 publications

    307 citations

  3. National Institute for Public Health and the Environment

    De Bilt, The Netherlands

    3 h-index

    9 publications

    438 citations

  4. National Center for Environmental Assessment (EPA)

    Cincinnati, United States

    3 h-index

    5 publications

    129 citations

  5. Brunel University of London

    London, United Kingdom

    3 h-index

    5 publications

    208 citations

  6. University of Southern California

    Los Angeles, United States

    3 h-index

    15 publications

    219 citations

  7. National Center for Toxicological Research

    Pine Bluff, United States

    2 h-index

    6 publications

    147 citations

  8. University of Florida

    Gainesville, United States

    2 h-index

    3 publications

    149 citations

1–8 of 50

Venues

  1. Toxicological Sciences

    3 publications · 131 citations

    3

    h-index

  2. Anesthesia & Analgesia

    2 publications · 25 citations

    2

    h-index

  3. Environmental Science & Technology

    2 publications · 116 citations

    2

    h-index

  4. Food and Chemical Toxicology

    2 publications · 106 citations

    2

    h-index

  5. Regulatory Toxicology and Pharmacology

    RTP · 2 publications · 86 citations

    2

    h-index

1–5