Dosage Sensitivity Analysis is a systematic experimental approach in reverse chemical genetics that assesses the phenotypic consequences of varying compound or drug concentrations to identify precise dosage thresholds linked to specific genetic perturbations.
36
Publications
4.3K
Citations
272
Authors
129
Institutions
Publications per year
2017–2026
14
Parents
Publications
36
Dosage sensitivity and the evolution of gene families in yeast
Balázs Papp, Csaba Pál, Laurence D. Hurst · Nature · 2003 · 861 citations
A cross-disorder dosage sensitivity map of the human genome
Ryan L. Collins, Joseph Glessner, Eleonora Porcu et al. · Cell · 2022 · 360 citations · Full text
1–5 of 36
Authors
272
- BL
3
h-index
- HH
2
h-index
- JF
2
h-index
- RGRosa García-Verdugo
Institució Catalana de Recerca i Estudis Avançats, Spain
2 publications · 409 citations
2
h-index
- JM
2
h-index
1–5 of 272
Institutions
129
Broad Institute
Cambridge, United States
5 h-index
47 publications
9.3K citations
Boston Children's Hospital
Boston, United States
4 h-index
5 publications
557 citations
Harvard University
Cambridge, United States
4 h-index
34 publications
5.2K citations
Massachusetts Institute of Technology
Cambridge, United States
3 h-index
34 publications
7K citations
Children's Hospital of Philadelphia
Philadelphia, United States
3 h-index
10 publications
1.3K citations
Brigham and Women's Hospital
Boston, United States
3 h-index
7 publications
719 citations
Massachusetts General Hospital
Boston, United States
3 h-index
37 publications
8.1K citations
Iowa State University
Ames, United States
2 h-index
2 publications
1.4K citations
1–8 of 129
Venues
- Cell
3 publications · 812 citations
3
h-index
- Genetics
3 publications · 72 citations
3
h-index
- Proceedings of the National Academy of Sciences
PNAS · 2 publications · 46 citations
2
h-index
- Journal of the American Statistical Association
2 publications · 1.4K citations
2
h-index
- PLoS Genetics
2 publications · 197 citations
2
h-index
1–5