Concepedia

Dnac-dependent Helicase Loading

DnaC-Dependent Helicase Loading is a molecular mechanism in bacterial DNA replication initiation wherein the DnaC protein mediates the ATP-dependent assembly of the DnaB helicase onto single-stranded DNA at the origin, thereby enabling replisome formation and unwinding of the DNA duplex.

35

Publications

2.2K

Citations

149

Authors

58

Institutions

Publications per year

2017–2026

7

Parents

Publications

35

Single-Molecule Studies of Origin Licensing Reveal Mechanisms Ensuring Bidirectional Helicase Loading

Simina Ticau, Larry J. Friedman, Nikola A. Ivica et al. · Cell · 2015 · 208 citations · Full text

, , +9

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1

Zuanning Yuan, Alberto Riera, Lin Bai et al. · Nature Structural & Molecular Biology · 2017 · 179 citations · Full text

, , +17

Formation of an ATP-DnaA-specific Initiation Complex Requires DnaA Arginine 285, a Conserved Motif in the AAA+ Protein Family

Hironori Kawakami, Kenji Keyamura, Tsutomu Katayama · Journal of Biological Chemistry · 2005 · 150 citations · Full text

, , +17

The DnaC helicase loader is a dual ATP/ADP switch protein

Megan J. Davey, Linhua Fang, Peter McInerney et al. · The EMBO Journal · 2002 · 137 citations · Full text

, , +9

A Two-Protein Strategy for the Functional Loading of a Cellular Replicative DNA Helicase

Marion Velten, Stephen McGovern, Stéphanie Marsin et al. · Molecular Cell · 2003 · 131 citations · Full text

, , +15

1–5 of 35

Authors

149

  1. TK
    Tsutomu Katayama

    Kyushu University, Japan

    5 publications · 430 citations

    5

    h-index

  2. NE
    Nicholas E. Dixon

    Australian National University, Australia

    4 publications · 158 citations

    4

    h-index

  3. JM
    James M. Berger

    University of California, Berkeley, United States

    3 publications · 135 citations

    3

    h-index

  4. PM
    Patrick M. Schaeffer

    James Cook University, Australia

    2 publications · 66 citations

    2

    h-index

  5. TU
    Tadashi Ueda

    Kyushu University, Japan

    2 publications · 130 citations

    2

    h-index

1–5 of 149

Institutions

58

  1. Kyushu University

    Fukuoka, Japan

    5 h-index

    19 publications

    1.3K citations

  2. Australian National University

    Canberra, Australia

    4 h-index

    11 publications

    368 citations

  3. Jawaharlal Nehru University

    New Delhi, India

    3 h-index

    9 publications

    242 citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    5 publications

    812 citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    6 publications

    1K citations

  6. Michigan State University

    East Lansing, United States

    2 h-index

    6 publications

    202 citations

  7. University of California, Berkeley

    Berkeley, United States

    2 h-index

    5 publications

    420 citations

  8. The Francis Crick Institute

    London, United Kingdom

    2 h-index

    3 publications

    296 citations

1–8 of 58

Venues

  1. Nucleic Acids Research

    8 publications · 351 citations

    8

    h-index

  2. Molecular Microbiology

    4 publications · 258 citations

    4

    h-index

  3. Journal of Biological Chemistry

    JBC · 4 publications · 313 citations

    4

    h-index

  4. eLife

    2 publications · 35 citations

    2

    h-index

  5. Biochemical Journal

    BJ · 2 publications · 59 citations

    2

    h-index

1–5