Concepedia

Dna Supercoiling Effects

DNA Supercoiling Effects is a theoretical construct in prokaryotic transcriptional regulation that characterizes the influence of topological DNA strain on gene expression dynamics by modulating RNA polymerase accessibility and promoter efficiency.

688

Publications

48.5K

Citations

1.8K

Authors

626

Institutions

Publications per year

2017–2026

93

Parents

Publications

688

Supercoiling of the DNA template during transcription.

Leroy F. Liu, J C Wang · Proceedings of the National Academy of Sciences · 1987 · 2K citations · Full text

, , +17

Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: Evidence for molecular models involving intercalation

Michael J. Waring · Journal of Molecular Biology · 1970 · 775 citations

, , +14

Transcription generates positively and negatively supercoiled domains in the template

Hai-Young Wu, Shihua Shyy, James C. Wang et al. · Cell · 1988 · 753 citations

, , +8

A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli

Christopher F. Higgins, Charles J. Dorman, Douglas A. Stirling et al. · Cell · 1988 · 716 citations

, , +17

DNA topology and its biological effects

Choice Reviews Online · 1991 · 609 citations

, , +14

1–5 of 688

Authors

1.8K

  1. CJ
    Charles J. Dorman

    Trinity College Dublin, Ireland

    15 publications · 2K citations

    15

    h-index

  2. KD
    Karl Drlica

    Rutgers, The State University of New Jersey, United States

    14 publications · 1.2K citations

    14

    h-index

  3. MD
    Marc Drolet

    Université de Montréal, Canada

    12 publications · 947 citations

    12

    h-index

  4. FL
    Fenfei Leng

    Florida International University, United States

    12 publications · 423 citations

    12

    h-index

  5. CJ
    Craig J. Benham

    University of California, Davis, United States

    12 publications · 753 citations

    12

    h-index

1–5 of 1.8K

Institutions

626

  1. Centre National de la Recherche Scientifique

    Paris, France

    26 h-index

    138 publications

    8.9K citations

  2. National Institutes of Health

    Bethesda, United States

    22 h-index

    75 publications

    5.6K citations

  3. University of California, Berkeley

    Berkeley, United States

    18 h-index

    45 publications

    5.6K citations

  4. University of Dundee

    Dundee, United Kingdom

    18 h-index

    48 publications

    7.4K citations

  5. National Cancer Institute

    Bethesda, United States

    17 h-index

    66 publications

    7K citations

  6. Johns Hopkins University

    Baltimore, United States

    15 h-index

    50 publications

    8.1K citations

  7. University of Alabama at Birmingham

    Birmingham, United States

    15 h-index

    36 publications

    2.7K citations

  8. Harvard University

    Cambridge, United States

    14 h-index

    34 publications

    5.2K citations

1–8 of 626

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 62 publications · 7.2K citations

    46

    h-index

  2. Nucleic Acids Research

    98 publications · 4.5K citations

    42

    h-index

  3. Molecular Microbiology

    58 publications · 3.5K citations

    39

    h-index

  4. Journal of Biological Chemistry

    JBC · 61 publications · 3.1K citations

    32

    h-index

  5. Journal of Bacteriology

    JB · 48 publications · 2.8K citations

    32

    h-index

1–5