Concepedia

Disorder-function Relationships

Disorder-Function Relationships is a theoretical construct in molecular biology that characterizes the causal and structural linkages between intrinsically disordered protein regions and their biological activities, distinguishing itself from ordered protein-function paradigms by emphasizing conformational flexibility as a functional determinant.

106

Publications

10.5K

Citations

447

Authors

179

Institutions

Publications per year

2017–2026

46

Parents

Publications

106

DisProt: the Database of Disordered Proteins

Megan D. Sickmeier, John A. Hamilton, Tanguy LeGall et al. · Nucleic Acids Research · 2006 · 810 citations · Full text

, , +16

D2P2: database of disordered protein predictions

Matt E. Oates, Pedro Romero, Takashi Ishida et al. · Nucleic Acids Research · 2012 · 730 citations · Full text

, , +15

Comparing and Combining Predictors of Mostly Disordered Proteins

Christopher J. Oldfield, Yugong Cheng, Marc S. Cortese et al. · Biochemistry · 2005 · 554 citations

, , +14

Intrinsically Disordered Proteins and Their “Mysterious” (Meta)Physics

Vladimir N. Uversky · Frontiers in Physics · 2019 · 547 citations · Full text

, , +17

Functional Anthology of Intrinsic Disorder. 3. Ligands, Post-Translational Modifications, and Diseases Associated with Intrinsically Disordered Proteins

Hongbo Xie, Slobodan Vučetić, Lilia M. Iakoucheva et al. · Journal of Proteome Research · 2007 · 384 citations · Full text

, , +17

1–5 of 106

Authors

447

  1. VN
    Vladimir N. Uversky

    University of South Florida, United States

    21 publications · 4.8K citations

    18

    h-index

  2. AK
    A. Keith Dunker

    Indiana University – Purdue University Indianapolis, United States

    12 publications · 3.8K citations

    11

    h-index

  3. ZO
    Zoran Obradović

    Temple University, United States

    10 publications · 3.1K citations

    10

    h-index

  4. CJ
    Christopher J. Oldfield

    Indiana University – Purdue University Indianapolis, United States

    9 publications · 2.2K citations

    9

    h-index

  5. PT
    Péter Tompa

    Institute of Molecular Life Sciences, Hungary

    8 publications · 1.6K citations

    8

    h-index

1–5 of 447

Institutions

179

  1. Institute for Biological Instrumentation

    Pushchino, Russia

    15 h-index

    33 publications

    10.3K citations

  2. University of South Florida

    Tampa, United States

    14 h-index

    35 publications

    2.2K citations

  3. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    13 h-index

    57 publications

    25.5K citations

  4. Indiana University School of Medicine

    Indianapolis, United States

    11 h-index

    36 publications

    12.3K citations

  5. Institute of Molecular Life Sciences

    Budapest, Hungary

    10 h-index

    42 publications

    15K citations

  6. USF Health Byrd Alzheimer's Institute

    Tampa, United States

    10 h-index

    10 publications

    1.3K citations

  7. Temple University

    Philadelphia, United States

    8 h-index

    28 publications

    7.8K citations

  8. Hungarian Academy of Sciences

    Budapest, Hungary

    8 h-index

    36 publications

    14.9K citations

1–8 of 179

Venues

  1. Molecular BioSystems

    8 publications · 429 citations

    8

    h-index

  2. Nucleic Acids Research

    8 publications · 2.3K citations

    7

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 6 publications · 145 citations

    6

    h-index

  4. PLoS ONE

    4 publications · 208 citations

    4

    h-index

  5. BMC Bioinformatics

    4 publications · 102 citations

    4

    h-index

1–5