Concepedia

Directed Random Mutagenesis

Directed Random Mutagenesis is a mutagenesis strategy that belongs to the class of random mutagenesis methods but is distinguished by the targeted localization of random mutations to a specific gene region or functional domain through controlled experimental design.

225

Publications

13.1K

Citations

960

Authors

331

Institutions

Publications per year

2017–2026

30

Parents

Publications

225

Directed evolution of a thermostable esterase

Lori Giver, Anne Gershenson, Per‐Ola Freskgård et al. · Proceedings of the National Academy of Sciences · 1998 · 530 citations

, , +17

Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors

Chao Li, Rui Zhang, Xiangbing Meng et al. · Nature Biotechnology · 2020 · 424 citations

, , +17

GFP‐like chromoproteins as a source of far‐red fluorescent proteins

Nadya G. Gurskaya, Arkady F. Fradkov, Alexey V. Terskikh et al. · FEBS Letters · 2001 · 259 citations

, , +16

Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for oxidation and transcriptional activation

I. Kullik, Michel B. Tolédano, Louis A. Tartaglia et al. · Journal of Bacteriology · 1995 · 244 citations · Full text

, , +16

A Highly Conserved Binding Site in Vesicle-associated Membrane Protein-associated Protein (VAP) for the FFAT Motif of Lipid-binding Proteins

Christopher Loewen, Tim P. Levine · Journal of Biological Chemistry · 2005 · 241 citations · Full text

, , +17

1–5 of 225

Authors

960

  1. FH
    Frances H. Arnold

    California Institute of Technology, United States

    6 publications · 1.1K citations

    6

    h-index

  2. US
    Ulrich Schwaneberg

    RWTH Aachen University, Germany

    3 publications · 216 citations

    3

    h-index

  3. SK
    Shigenori Kanaya

    The University of Osaka, Japan

    3 publications · 92 citations

    3

    h-index

  4. DG
    David González-Pérez

    Instituto de Catálisis y Petroleoquímica, Spain

    3 publications · 97 citations

    3

    h-index

  5. TS
    Tuck Seng Wong

    University of Sheffield, United Kingdom

    3 publications · 207 citations

    3

    h-index

1–5 of 960

Institutions

331

  1. Chinese Academy of Sciences

    Beijing, China

    7 h-index

    26 publications

    4.2K citations

  2. The University of Osaka

    Osaka, Japan

    7 h-index

    22 publications

    465 citations

  3. Scripps Research Institute

    San Diego, United States

    6 h-index

    23 publications

    3.2K citations

  4. California Institute of Technology

    Pasadena, United States

    6 h-index

    21 publications

    4.1K citations

  5. University of Stuttgart

    Stuttgart, Germany

    5 h-index

    8 publications

    614 citations

  6. University of Groningen

    Groningen, The Netherlands

    4 h-index

    6 publications

    466 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    21 publications

    704 citations

  8. Kyoto University

    Kyoto, Japan

    4 h-index

    9 publications

    536 citations

1–8 of 331

Venues

  1. Journal of Biological Chemistry

    JBC · 18 publications · 1.2K citations

    17

    h-index

  2. Protein Engineering Design and Selection

    PEDS · 18 publications · 829 citations

    15

    h-index

  3. Journal of Molecular Biology

    JMB · 9 publications · 770 citations

    9

    h-index

  4. Applied Microbiology and Biotechnology

    9 publications · 392 citations

    9

    h-index

  5. Applied and Environmental Microbiology

    AEM · 8 publications · 515 citations

    8

    h-index

1–5