Concepedia

Directed Point Mutagenesis

Directed Point Mutagenesis is a molecular biology technique that belongs to the broader category of site-directed mutagenesis methods, distinguished by its precise alteration of a single nucleotide residue within a defined DNA sequence to generate a specific, predetermined mutation.

172

Publications

10.9K

Citations

764

Authors

261

Institutions

Publications per year

2017–2026

10

Parents

Publications

172

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

Mark J. Zoller, Michael J. Smith · Nucleic Acids Research · 1982 · 762 citations · Full text

, , +17

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

Mark P. Kamps, J E Buss, Bartholomew M. Sefton · Proceedings of the National Academy of Sciences · 1985 · 379 citations · Full text

, , +14

Genetic Analysis of Histone H4: Essential Role of Lysines Subject to Reversible Acetylation

Paul C. Megee, Brian A. Morgan, Barbara A. Mittman et al. · Science · 1990 · 347 citations

, , +13

Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth

Hongjie Wang, Yoshiyuki Rikitake, Mary Corrigan Carter et al. · Journal of Virology · 1993 · 255 citations · Full text

, , +17

Glycosylation at specific sites of erythropoietin is essential for biosynthesis, secretion, and biological function.

Shishir Dube, J. W. Fisher, Jerry S. Powell · Journal of Biological Chemistry · 1988 · 232 citations · Full text

, , +17

1–5 of 172

Authors

764

  1. CP
    Cindy Putnam‐Evans

    East Carolina University, United States

    4 publications · 155 citations

    4

    h-index

  2. TB
    Terry Bricker

    Louisiana State University, United States

    4 publications · 155 citations

    4

    h-index

  3. FP
    Francisco Portillo

    Universidad Autónoma de Madrid, Spain

    3 publications · 289 citations

    3

    h-index

  4. RS
    Ramón Serrano

    Instituto de Biología Molecular y Celular de Plantas, Spain

    3 publications · 289 citations

    3

    h-index

  5. SP
    Susan Pesce

    Memorial Sloan Kettering Cancer Center, United States

    2 publications · 114 citations

    2

    h-index

1–5 of 764

Institutions

261

  1. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    43 publications

    1.4K citations

  2. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    5 h-index

    21 publications

    2.1K citations

  3. Louisiana State University

    Baton Rouge, United States

    5 h-index

    16 publications

    589 citations

  4. University of California, Los Angeles

    Los Angeles, United States

    4 h-index

    13 publications

    791 citations

  5. Sorbonne Université

    Paris, France

    4 h-index

    27 publications

    600 citations

  6. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    12 publications

    661 citations

  7. National Institutes of Health

    Bethesda, United States

    4 h-index

    11 publications

    745 citations

  8. East Carolina University

    Greenville, United States

    3 h-index

    12 publications

    455 citations

1–8 of 261

Venues

  1. Journal of Biological Chemistry

    JBC · 28 publications · 1.8K citations

    23

    h-index

  2. Journal of Virology

    JVI · 12 publications · 879 citations

    12

    h-index

  3. Biochemistry

    12 publications · 460 citations

    11

    h-index

  4. Journal of Bacteriology

    JB · 9 publications · 371 citations

    9

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 1.2K citations

    9

    h-index

1–5