Concepedia

Directed Library Evolution

Directed Library Evolution is a methodological framework within diversity generation and library construction that systematically designs and iteratively optimizes molecular or functional libraries through targeted perturbations and selection pressures to achieve desired phenotypic or functional outcomes.

8

Publications

197

Citations

37

Authors

15

Institutions

Publications per year

2017–2026

2

Parents

Publications

8

Error-Prone PCR and Effective Generation of Gene Variant Libraries for Directed Evolution

Janine N. Copp, Paulina Hanson‐Manful, David F. Ackerley et al. · Methods in molecular biology · 2014 · 72 citations

, , +15

Pooling for Improved Screening of Combinatorial Libraries for Directed Evolution

Karen M. Polizzi, Monal R. Parikh, Cody U. Spencer et al. · Biotechnology Progress · 2006 · 32 citations

, , +17

Combining Random Gene Fission and Rational Gene Fusion To Discover Near-Infrared Fluorescent Protein Fragments That Report on Protein–Protein Interactions

Naresh Pandey, Christopher L. Nobles, Lynn Zechiedrich et al. · ACS Synthetic Biology · 2014 · 25 citations · Full text

, , +13

AXM mutagenesis: An efficient means for the production of libraries for directed evolution of proteins

Erika G. Holland, Diane L. Buhr, Felicity E. Acca et al. · Journal of Immunological Methods · 2013 · 18 citations

, , +16

Probabilistic Methods in Directed Evolution: Library Size, Mutation Rate, and Diversity

Yuval Nov · Methods in molecular biology · 2014 · 14 citations

, , +15

1–5 of 8

Authors

37

  1. EG
    Erika G. Holland

    University of Illinois Chicago, United States

    1 publications · 18 citations

    1

    h-index

  2. MC
    Matthew Charles Edmundson

    University of Edinburgh, United Kingdom

    1 publications · 11 citations

    1

    h-index

  3. JN
    Janine N. Copp

    Victoria University of Wellington, New Zealand

    1 publications · 72 citations

    1

    h-index

  4. CA
    Christopher A. Voigt

    Massachusetts Institute of Technology, United States

    1 publications · 13 citations

    1

    h-index

  5. JA
    James A. J. Arpino

    Cardiff University, United Kingdom

    1 publications · 11 citations

    1

    h-index

1–5 of 37

Institutions

15

  1. AxioMx (United States)

    Branford, United States

    1 h-index

    8 publications

    144 citations

  2. Baylor College of Medicine

    Houston, United States

    1 h-index

    3 publications

    75 citations

  3. University of Haifa

    Haifa, Israel

    1 h-index

    1 publications

    14 citations

  4. University of Illinois Chicago

    Chicago, United States

    1 h-index

    1 publications

    18 citations

  5. Rice University

    Houston, United States

    1 h-index

    3 publications

    75 citations

  6. University of British Columbia

    Vancouver, Canada

    1 h-index

    1 publications

    72 citations

  7. Canada's Michael Smith Genome Sciences Centre

    Vancouver, Canada

    1 h-index

    1 publications

    72 citations

  8. Georgia Institute of Technology

    Atlanta, United States

    1 h-index

    5 publications

    160 citations

1–8 of 15

Venues

  1. Methods in molecular biology

    Book series · 3 publications · 97 citations

    3

    h-index

  2. Methods in enzymology on CD-ROM/Methods in enzymology

    Book series · 1 publications · 12 citations

    1

    h-index

  3. Biotechnology Progress

    1 publications · 32 citations

    1

    h-index

  4. Journal of Immunological Methods

    1 publications · 18 citations

    1

    h-index

  5. ACS Synthetic Biology

    1 publications · 25 citations

    1

    h-index

1–5