Directed Evolution Of Binding Elements
Directed Evolution of Binding Elements is a laboratory method that systematically mimics natural evolutionary processes through iterative rounds of genetic diversification and selection to engineer high-affinity biorecognition elements with tailored binding specificities.
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Continuous directed evolution of DNA-binding proteins to improve TALEN specificity
Basil P. Hubbard, Ahmed H. Badran, John A. Zuris et al. · Nature Methods · 2015 · 124 citations · Full text
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Pioneer Hi-Bred
Johnston, United States
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1 publications
124 citations

Howard Hughes Medical Institute
Chevy Chase, United States
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1 publications
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Center for Cancer Research
Bethesda, United States
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3 publications
372 citations
Harvard University
Cambridge, United States
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10 publications
1.2K citations
Massachusetts General Hospital
Boston, United States
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372 citations
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