Concepedia

Digital Molecular Detection

Digital Molecular Detection is a molecular diagnostic method that leverages digital amplification and sequencing technologies to enable highly sensitive, quantitative detection of nucleic acids at the point of care, distinguishing itself through discrete, single-molecule resolution and data-driven analysis.

70

Publications

4.8K

Citations

435

Authors

164

Institutions

Publications per year

2017–2026

46

Variants

Digital Molecular Diagnostics

Parents

Publications

70

Integrated digital error suppression for improved detection of circulating tumor DNA

Aaron M. Newman, Alexander F. Lovejoy, Daniel M. Klass et al. · Nature Biotechnology · 2016 · 1.1K citations

, , +16

An Ultralocalized Cas13a Assay Enables Universal and Nucleic Acid Amplification-Free Single-Molecule RNA Diagnostics

Tian Tian, Bowen Shu, Yongzhong Jiang et al. · ACS Nano · 2020 · 321 citations

, , +14

High-Performance Single Cell Genetic Analysis Using Microfluidic Emulsion Generator Arrays

Yong Zeng, Richard Novák, Joe Shuga et al. · Analytical Chemistry · 2010 · 233 citations

, , +17

Multiplexed Quantification of Nucleic Acids with Large Dynamic Range Using Multivolume Digital RT-PCR on a Rotational SlipChip Tested with HIV and Hepatitis C Viral Load

Feng Shen, Bing Sun, Jason E. Kreutz et al. · Journal of the American Chemical Society · 2011 · 230 citations · Full text

, , +17

Single molecule detection in nanofluidic digital array enables accurate measurement of DNA copy number

Somanath Bhat, Jan Herrmann, Paul Armishaw et al. · Analytical and Bioanalytical Chemistry · 2009 · 224 citations

, , +15

1–5 of 70

Authors

435

  1. JW
    Jian Wu

    Zhejiang University, China

    2 publications · 122 citations

    2

    h-index

  2. QR
    Qingyu Ruan

    Collaborative Innovation Center of Chemistry for Energy Materials, China

    2 publications · 92 citations

    2

    h-index

  3. JJ
    Jingcheng Ji

    Xi'an Jiaotong University, China

    2 publications · 36 citations

    2

    h-index

  4. ZL
    Zedong Li

    Xi'an Jiaotong University, China

    2 publications · 36 citations

    2

    h-index

  5. FS
    Feng Shen

    Shanghai Jiao Tong University, China

    2 publications · 273 citations

    2

    h-index

1–5 of 435

Institutions

164

  1. Zhejiang University

    Hangzhou, China

    4 h-index

    25 publications

    1.5K citations

  2. Wuhan University

    Wuhan, China

    3 h-index

    9 publications

    649 citations

  3. Xi'an Jiaotong University

    Xi'an, China

    3 h-index

    14 publications

    244 citations

  4. Harvard University

    Cambridge, United States

    3 h-index

    10 publications

    820 citations

  5. University of Hong Kong

    Pok Fu Lam, Hong Kong

    3 h-index

    5 publications

    222 citations

  6. Fred Hutch Cancer Center

    Seattle, United States

    2 h-index

    8 publications

    195 citations

  7. Tsinghua University

    Beijing, China

    2 h-index

    10 publications

    350 citations

  8. Changsha University

    Changsha, China

    2 h-index

    10 publications

    308 citations

1–8 of 164

Venues

  1. Biosensors and Bioelectronics

    5 publications · 342 citations

    7

    h-index

  2. Analytical Chemistry

    6 publications · 536 citations

    6

    h-index

  3. Lab on a Chip

    5 publications · 186 citations

    5

    h-index

  4. Chemical Communications

    ChemComm · 4 publications · 90 citations

    4

    h-index

  5. Scientific Reports

    2 publications · 73 citations

    2

    h-index

1–5