Concepedia

Differentiation Inhibition

Differentiation Inhibition is a regulatory mechanism in developmental biology that belongs to the class of cell differentiation controls and is distinguished by its function in actively suppressing the progression of undifferentiated cells into specialized cell types, thereby maintaining cellular pluripotency or progenitor states.

199

Publications

13.8K

Citations

1.3K

Authors

437

Institutions

Publications per year

2017–2026

47

Parents

Publications

199

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Martin Göttlicher · The EMBO Journal · 2001 · 1.9K citations · Full text

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Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

Raymond P. Warrell, Stanley R. Frankel, Wilson H. Miller et al. · New England Journal of Medicine · 1991 · 1.3K citations · Full text

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All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments]

Sylvie Castaigné, Christine Chomienne, MT Daniel et al. · Blood · 1990 · 1.2K citations · Full text

, , +11

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

Victoria M. Richon, Yael Webb, R Merger et al. · Proceedings of the National Academy of Sciences · 1996 · 421 citations

, , +13

Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

Ina Oehme, Hedwig E. Deubzer, Dennis Wegener et al. · Clinical Cancer Research · 2008 · 401 citations · Full text

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1–5 of 199

Authors

1.3K

  1. GY
    Guangmei Yan

    Sun Yat-sen University, China

    5 publications · 283 citations

    5

    h-index

  2. CM
    Consolación Melguizo

    Universidad de Granada, Spain

    4 publications · 56 citations

    4

    h-index

  3. JP
    José Prados

    Universidad de Granada, Spain

    4 publications · 56 citations

    4

    h-index

  4. JA
    Juan Antonio Marchal

    Universidad de Granada, Spain

    4 publications · 49 citations

    4

    h-index

  5. EM
    Eytan M. Stein

    Memorial Sloan Kettering Cancer Center, United States

    3 publications · 227 citations

    3

    h-index

1–5 of 1.3K

Institutions

437

  1. Sun Yat-sen University

    Guangzhou, China

    8 h-index

    75 publications

    5.2K citations

  2. Memorial Sloan Kettering Cancer Center

    New York, United States

    7 h-index

    24 publications

    13.8K citations

  3. Heidelberg University

    Heidelberg, Germany

    6 h-index

    27 publications

    2K citations

  4. Harvard University

    Cambridge, United States

    6 h-index

    17 publications

    1.2K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    5 h-index

    11 publications

    698 citations

  6. German Cancer Research Center

    Heidelberg, Germany

    5 h-index

    23 publications

    1.1K citations

  7. Universidad de Granada

    Granada, Spain

    5 h-index

    26 publications

    356 citations

  8. Shanghai Jiao Tong University

    Shanghai, China

    4 h-index

    19 publications

    709 citations

1–8 of 437

Venues

  1. PubMed

    Repository · 26 publications · 1.3K citations

    19

    h-index

  2. PLoS ONE

    8 publications · 285 citations

    8

    h-index

  3. Scientific Reports

    7 publications · 191 citations

    7

    h-index

  4. International Journal of Oncology

    6 publications · 194 citations

    6

    h-index

  5. Blood

    5 publications · 1.5K citations

    5

    h-index

1–5