Concepedia

Detoxication Mechanisms

Detoxication Mechanisms is a biochemical process category within xenobiotic metabolism that functions to convert carcinogens into less reactive, more water-soluble compounds through enzymatic transformations, thereby facilitating their excretion and reducing potential cellular damage.

669

Publications

41.1K

Citations

2K

Authors

619

Institutions

Publications per year

2017–2026

57

Variants

Detoxification Mechanisms

Parents

Publications

669

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.

Yuesheng Zhang, Paul Talalay, C G Cho et al. · Proceedings of the National Academy of Sciences · 1992 · 1.7K citations

, , +16

Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

Jed W. Fahey, Yuesheng Zhang, Paul Talalay · Proceedings of the National Academy of Sciences · 1997 · 1.4K citations · Full text

, , +14

DETOXICATION MECHANISMS

E. Browning · BMJ · 1960 · 763 citations · Full text

, , +15

Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates.

Yuesheng Zhang, Thomas W. Kensler, C G Cho et al. · Proceedings of the National Academy of Sciences · 1994 · 751 citations · Full text

, , +17

Biodegradation of Chemicals of Environmental Concern

Martin Alexander · Science · 1981 · 689 citations

, , +16

1–5 of 669

Authors

2K

  1. JN
    J. N. Smith

    Bedford Institute of Oceanography, Canada

    27 publications · 1.1K citations

    21

    h-index

  2. RT
    R. T. Williams

    St Mary's Hospital, United Kingdom

    24 publications · 1.2K citations

    19

    h-index

  3. DV
    D. V. Parke

    St Mary's Hospital, United Kingdom

    17 publications · 1.1K citations

    16

    h-index

  4. SP
    Stephan Pflugmacher

    Leibniz Institute of Freshwater Ecology and Inland Fisheries, Germany

    16 publications · 1.1K citations

    15

    h-index

  5. RT
    R. T. Williams

    St. Mary's Hospital, United Kingdom

    14 publications · 827 citations

    14

    h-index

1–5 of 2K

Institutions

619

  1. St Mary's Hospital

    Kettering, United Kingdom

    32 h-index

    122 publications

    6.5K citations

  2. Johns Hopkins University

    Baltimore, United States

    19 h-index

    65 publications

    24.3K citations

  3. Leibniz Institute of Freshwater Ecology and Inland Fisheries

    Berlin, Germany

    15 h-index

    40 publications

    3.4K citations

  4. St. Mary's Hospital

    Portsmouth, United Kingdom

    15 h-index

    40 publications

    2.3K citations

  5. Charles University

    Prague, Czechia

    12 h-index

    35 publications

    1.2K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    44 publications

    1.7K citations

  7. German Cancer Research Center

    Heidelberg, Germany

    10 h-index

    20 publications

    602 citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    10 h-index

    24 publications

    16.8K citations

1–8 of 619

Venues

  1. Biochemical Journal

    56 publications · 2.6K citations

    32

    h-index

  2. PubMed

    Repository · 55 publications · 4K citations

    25

    h-index

  3. Journal of Biological Chemistry

    JBC · 17 publications · 1.8K citations

    15

    h-index

  4. Pesticide Biochemistry and Physiology

    PBP · 14 publications · 821 citations

    14

    h-index

  5. Chemical Research in Toxicology

    17 publications · 640 citations

    13

    h-index

1–5