Concepedia

Desmoglein Autoimmunity

Desmoglein Autoimmunity is an autoimmune pathology characterized by the immune system's production of autoantibodies specifically targeting desmogleins, a subset of desmosomal cadherins essential for epithelial cell adhesion, thereby distinguishing it from other autoimmune disorders by its molecular specificity and associated blistering dermatological manifestations.

308

Publications

17.9K

Citations

1.3K

Authors

391

Institutions

Publications per year

2017–2026

52

Parents

Publications

308

Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins

Ken Ishii, Masayuki Amagai, Russell P. Hall et al. · The Journal of Immunology · 1997 · 481 citations · Full text

, , +17

Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris

Mỹ G. Mahoney, Zhihong Wang, Kyle Rothenberger et al. · Journal of Clinical Investigation · 1999 · 473 citations · Full text

, , +17

The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile

Masayuki Amagai, Kazuyuki Tsunoda, Detlef Zillikens et al. · Journal of the American Academy of Dermatology · 1999 · 418 citations

, , +9

Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting

Liat Samuelov, Ofer Sarig, Robert M. Harmon et al. · Nature Genetics · 2013 · 334 citations · Full text

, , +13

Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice.

Masayuki Amagai, T. Níshikaẃa, Hossein C. Nousari et al. · Journal of Clinical Investigation · 1998 · 316 citations · Full text

, , +17

1–5 of 308

Authors

1.3K

  1. MA
    Masayuki Amagai

    Keio University, Japan

    69 publications · 6.4K citations

    41

    h-index

  2. TH
    Takashi Hashimoto

    Kurume University, Japan

    38 publications · 2.6K citations

    26

    h-index

  3. JR
    John R. Stanley

    National Cancer Institute, United States

    23 publications · 2.6K citations

    20

    h-index

  4. MH
    Michael Hertl

    Philipps University of Marburg, Germany

    24 publications · 1.4K citations

    20

    h-index

  5. KI
    Ken Ishii

    Keio University, Japan

    18 publications · 1.6K citations

    17

    h-index

1–5 of 1.3K

Institutions

391

  1. Keio University

    Tokyo, Japan

    37 h-index

    187 publications

    19.9K citations

  2. Kurume University

    Kurume, Japan

    22 h-index

    96 publications

    5.4K citations

  3. University of Pennsylvania

    Philadelphia, United States

    21 h-index

    88 publications

    9.5K citations

  4. Philipps University of Marburg

    Marburg, Germany

    17 h-index

    62 publications

    3.7K citations

  5. Medical College of Wisconsin

    Milwaukee, United States

    14 h-index

    51 publications

    5.7K citations

  6. Keio University Hospital

    Tokyo, Japan

    13 h-index

    55 publications

    9K citations

  7. University of Lübeck

    Lübeck, Germany

    12 h-index

    59 publications

    3.6K citations

  8. University of Würzburg

    Würzburg, Germany

    12 h-index

    36 publications

    3.5K citations

1–8 of 391

Venues

  1. Journal of Investigative Dermatology

    JID · 28 publications · 2K citations

    24

    h-index

  2. British Journal of Dermatology

    36 publications · 1.9K citations

    24

    h-index

  3. The Journal of Immunology

    JI · 18 publications · 1.8K citations

    17

    h-index

  4. Frontiers in Immunology

    17 publications · 416 citations

    15

    h-index

  5. PubMed

    Repository · 16 publications · 766 citations

    15

    h-index

1–5