Revealing modular organization in the yeast transcriptional network

Jan Ihmels, Gilgi Friedlander, Sven Bergmann, +3

Nature Genetics

Functional GenomicsBiological NetworkMolecular BiologyRegulatory Network ModellingGene Regulatory Network +3

Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting

Liat Samuelov, Ofer Sarig, Robert M. Harmon, +22

Nature Genetics

AllergyAutoimmune DiseaseAtopic DermatitisDesmoglein 1Allergen +7

Familial Pityriasis Rubra Pilaris Is Caused by Mutations in CARD14

Dana Fuchs‐Telem, Ofer Sarig, Maurice A. M. Van Steensel, +11

The American Journal of Human Genetics

Genetic DisorderGeneticsPathogenesisPathologyMolecular Genetics +2

Variant <i>PADI3</i> in Central Centrifugal Cicatricial Alopecia

Liron Malki, Ofer Sarig, Maria-Teresa Romano, +18

New England Journal of Medicine

Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation

Robert M. Harmon, Cory L. Simpson, Jodi Johnson, +6

Journal of Clinical Investigation

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseAutophagyYeast 2-Hybrid Screen +8

Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility

Zhimiao Lin, Shuo Li, Cheng Feng, +24

Nature Genetics

Human Skin FragilitySkin DevelopmentCutaneous BiologyDermatologyMedicine +2

Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

Maeve A. McAleer, Elizabeth Pöhler, Frances J.D. Smith, +17

Journal of Allergy and Clinical Immunology

RIN2 Deficiency Results in Macrocephaly, Alopecia, Cutis Laxa, and Scoliosis: MACS Syndrome

Lina Basel‐Vanagaite, Ofer Sarig, Dov Hershkovitz, +17

The American Journal of Human Genetics

Cutis LaxaPathologyDermatologyMacs SyndromeMedicine +2

Population-Specific Association between a Polymorphic Variant in ST18, Encoding a Pro-Apoptotic Molecule, and Pemphigus Vulgaris

Ofer Sarig, Sivan Bercovici, Lilach Zoller, +22

Journal of Investigative Dermatology

BiologyGenetic DiversityAllelic VariantPhylogeneticsBiochemical Taxonomy +13

CEDNIK syndrome results from loss-of-function mutations in SNAP29

Dana Fuchs‐Telem, Helen Stewart, David Rapaport, +13

British Journal of Dermatology