Concepedia

Delta-notch Interactions

Delta-Notch Interactions is a cell signaling mechanism in developmental biology wherein the Delta ligand on the surface of one cell binds to the Notch receptor on an adjacent cell, triggering a proteolytic cascade that regulates gene expression to control cell fate decisions through lateral inhibition or inductive signaling.

293

Publications

30.8K

Citations

1.3K

Authors

443

Institutions

Publications per year

2017–2026

38

Variants

Delta-notch Signaling

Parents

Publications

293

Mind Bomb Is a Ubiquitin Ligase that Is Essential for Efficient Activation of Notch Signaling by Delta

Motoyuki Itoh, Cheol‐Hee Kim, Gregory R. Palardy et al. · Developmental Cell · 2003 · 782 citations · Full text

, , +13

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

Ilaria Rebay, R.J. Fleming, Richard G. Fehon et al. · Cell · 1991 · 774 citations

, , +9

Glycosyltransferase activity of Fringe modulates Notch–Delta interactions

Katja Brückner, Lídia Pérez, Henrik Clausen et al. · Nature · 2000 · 685 citations

, , +11

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

Richard G. Fehon, Pamela J. Kooh, Ilaria Rebay et al. · Cell · 1990 · 676 citations

, , +13

Multipotent <i>Drosophila</i> Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling

Benjamin Ohlstein, Allan C. Spradling · Science · 2007 · 660 citations

, , +17

1–5 of 293

Authors

1.3K

  1. JL
    Julian Lewis

    The Honourable Society of Lincoln's Inn, United Kingdom

    9 publications · 2.6K citations

    9

    h-index

  2. MA
    Marc A. T. Muskavitch

    Indiana University Bloomington, United States

    9 publications · 1.5K citations

    9

    h-index

  3. SA
    Spyros Artavanis‐Tsakonas

    Harvard University, United States

    7 publications · 1.8K citations

    7

    h-index

  4. ID
    Irwin D. Bernstein

    Fred Hutch Cancer Center, United States

    6 publications · 758 citations

    6

    h-index

  5. MH
    Martin Hrabě de Angelis

    Helmholtz Zentrum München, Germany

    6 publications · 838 citations

    6

    h-index

1–5 of 1.3K

Institutions

443

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    24 h-index

    80 publications

    25.1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    23 h-index

    95 publications

    12.1K citations

  3. Inserm

    Paris, France

    17 h-index

    74 publications

    6.8K citations

  4. Indiana University Bloomington

    Bloomington, United States

    9 h-index

    25 publications

    5.2K citations

  5. University of Washington

    Seattle, United States

    9 h-index

    31 publications

    3K citations

  6. Harvard University

    Cambridge, United States

    8 h-index

    16 publications

    2.9K citations

  7. University of Oxford

    Oxford, United Kingdom

    8 h-index

    47 publications

    8.9K citations

  8. University of Cambridge

    Cambridge, United Kingdom

    8 h-index

    20 publications

    2.2K citations

1–8 of 443

Venues

  1. Development

    58 publications · 6.3K citations

    47

    h-index

  2. PLoS ONE

    12 publications · 474 citations

    12

    h-index

  3. Developmental Biology

    11 publications · 601 citations

    11

    h-index

  4. Blood

    11 publications · 1.5K citations

    11

    h-index

  5. Journal of Biological Chemistry

    JBC · 9 publications · 1.1K citations

    9

    h-index

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