Concepedia

Deferoxamine Toxicity

Deferoxamine Toxicity is a clinical phenomenon characterized by adverse physiological effects arising from the accumulation or administration of deferoxamine, a siderophore-based chelating agent, distinguished from other drug-related toxicities by its specific association with iron chelation therapy and its impact on cellular metabolism, microbial susceptibility, and organ function.

95

Publications

4.8K

Citations

419

Authors

173

Institutions

Publications per year

2017–2026

12

Parents

Publications

95

Visual and Auditory Neurotoxicity in Patients Receiving Subcutaneous Deferoxamine Infusions

Nancy F. Olivieri, J. Raymond Buncic, Emily Chew et al. · New England Journal of Medicine · 1986 · 431 citations

, , +17

Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies.

Johan R. Boelaert, M. de Locht, J. Van Cutsem et al. · Journal of Clinical Investigation · 1993 · 343 citations · Full text

, , +17

Hemoglobin- and myoglobin-induced acute renal failure in rats: role of iron in nephrotoxicity

Mark S. Paller · American Journal of Physiology-Renal Physiology · 1988 · 294 citations

, , +17

Effects of a single course of deferoxamine in neuroblastoma patients.

Alberto Donfrancesco, G Deb, C Dominici et al. · PubMed · 1990 · 197 citations

, , +15

Modulation of deferoxamine toxicity and clearance by covalent attachment to biocompatible polymers.

Philip E. Hallaway, John W. Eaton, S. Scott Panter et al. · Proceedings of the National Academy of Sciences · 1989 · 189 citations · Full text

, , +17

1–5 of 95

Authors

419

  1. GJ
    George J. Kontoghiorghes

    University College London, United Kingdom

    7 publications · 222 citations

    7

    h-index

  2. MH
    Melvin H. Freedman

    Hospital for Sick Children, Canada

    4 publications · 533 citations

    4

    h-index

  3. LH
    Lawrence Helson

    Memorial Sloan Kettering Cancer Center, United States

    3 publications · 275 citations

    3

    h-index

  4. NF
    Nancy F. Olivieri

    Hospital for Sick Children, Canada

    3 publications · 505 citations

    3

    h-index

  5. MT
    Meng Tian

    Sichuan University, China

    3 publications · 62 citations

    3

    h-index

1–5 of 419

Institutions

173

  1. Hospital for Sick Children

    Toronto, Canada

    5 h-index

    24 publications

    5.6K citations

  2. University College London

    London, United Kingdom

    4 h-index

    12 publications

    358 citations

  3. University of Michigan

    Ann Arbor, United States

    4 h-index

    8 publications

    175 citations

  4. University of Toronto

    Toronto, Canada

    4 h-index

    14 publications

    476 citations

  5. West China Hospital of Sichuan University

    Chengdu, China

    3 h-index

    16 publications

    283 citations

  6. Sichuan University

    Chengdu, China

    3 h-index

    22 publications

    463 citations

  7. Washington Poison Center

    Seattle, United States

    3 h-index

    6 publications

    95 citations

  8. AZ Sint-Jan

    Bruges, Belgium

    2 h-index

    8 publications

    2.6K citations

1–8 of 173

Venues

  1. PubMed

    Repository · 16 publications · 765 citations

    13

    h-index

  2. Journal of Toxicology Clinical Toxicology

    2 publications · 53 citations

    2

    h-index

  3. Brain Research

    2 publications · 49 citations

    2

    h-index

  4. Retina

    2 publications · 100 citations

    2

    h-index

  5. Toxicology and Applied Pharmacology

    TAAP · 2 publications · 112 citations

    2

    h-index

1–5