Concepedia

Dead-end Elimination

Dead-End Elimination is a computational optimization algorithm in the field of protein side-chain prediction that prunes rotamer conformations incompatible with the global energy minimum by systematically eliminating assignments that cannot contribute to the optimal solution.

59

Publications

4.3K

Citations

131

Authors

62

Institutions

Publications per year

2017–2026

5

Variants

Dee

Parents

Publications

59

The dead-end elimination theorem and its use in protein side-chain positioning

Johan Desmet, Marc De Maeyer, Bart Hazes et al. · Nature · 1992 · 696 citations

, , +9

The C information abstraction system

Y.-F. Chen, Michael Nishimoto, C. V. Ramamoorthy · IEEE Transactions on Software Engineering · 1990 · 279 citations

, , +15

Exploring the conformational space of protein side chains using dead-end elimination and the A* algorithm

Andrew R. Leach, Andrew P. Lemon · Proteins Structure Function and Bioinformatics · 1998 · 224 citations

, , +16

Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics

Loren L. Looger, Homme W. Hellinga · Journal of Molecular Biology · 2001 · 202 citations

, , +15

Partial dead code elimination

Jens Knoop, Oliver Rüthing, Bernhard Steffen · 1994 · 191 citations

, , +9

1–5 of 59

Authors

131

  1. IL
    Ignace Lasters

    KU Leuven, Belgium

    7 publications · 1.2K citations

    7

    h-index

  2. BR
    Bruce R. Donald

    Duke University, United States

    6 publications · 469 citations

    6

    h-index

  3. JD
    Johan Desmet

    KU Leuven, Belgium

    6 publications · 1.2K citations

    6

    h-index

  4. SL
    Stephen L. Mayo

    California Institute of Technology, United States

    5 publications · 464 citations

    5

    h-index

  5. MD
    Marc De Maeyer

    KU Leuven, Belgium

    5 publications · 1K citations

    5

    h-index

1–5 of 131

Institutions

62

  1. KU Leuven

    Leuven, Belgium

    7 h-index

    13 publications

    1.7K citations

  2. Duke Medical Center

    Durham, United States

    6 h-index

    17 publications

    1.5K citations

  3. Duke University Hospital

    Durham, United States

    6 h-index

    17 publications

    1.5K citations

  4. Duke University

    Durham, United States

    5 h-index

    13 publications

    1.1K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    5 publications

    464 citations

  6. California Institute of Technology

    Pasadena, United States

    5 h-index

    12 publications

    1.1K citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    8 publications

    358 citations

  8. Vlaams Instituut voor Biotechnologie

    Ghent, Belgium

    3 h-index

    4 publications

    438 citations

1–8 of 62

Venues

  1. Journal of Computational Chemistry

    10 publications · 699 citations

    10

    h-index

  2. Bioinformatics

    6 publications · 261 citations

    6

    h-index

  3. Protein Engineering Design and Selection

    PEDS · 4 publications · 255 citations

    4

    h-index

  4. Proteins Structure Function and Bioinformatics

    4 publications · 506 citations

    4

    h-index

  5. ACM SIGPLAN Notices

    3 publications · 70 citations

    3

    h-index

1–5