Concepedia

Datp Dependence

DATP Dependence is a biochemical requirement in the context of apoptosome formation, referring to the specific necessity of deoxyadenosine triphosphate (dATP) as a nucleotide cofactor for the oligomerization and activation of the Apaf-1 protein into a functional apoptosome complex.

40

Publications

14.9K

Citations

173

Authors

57

Institutions

Publications per year

2017–2026

0

Parents

Publications

40

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

, , +17

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Xuesong Liu, Caryn Naekyung Kim, Jie Yang et al. · Cell · 1996 · 5.2K citations · Full text

, , +10

Mechanism and fidelity of HIV reverse transcriptase.

Warren M. Kati, Kenneth A. Johnson, L. Fred Jerva et al. · Journal of Biological Chemistry · 1992 · 491 citations · Full text

, , +17

Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.

Volker Heinemann, Yi-Zheng Xu, Sherri Chubb et al. · Molecular Pharmacology · 1990 · 407 citations

, , +13

Quantitation of cellular deoxynucleoside triphosphates

Paola Ferraro, Elisa Franzolin, Giovanna Pontarin et al. · Nucleic Acids Research · 2009 · 167 citations · Full text

, , +16

1–5 of 40

Authors

173

  1. JG
    James G. Vaughn

    University of Oklahoma, United States

    2 publications · 74 citations

    2

    h-index

  2. KG
    K. Ganeshaguru

    The Royal Free Hospital, United Kingdom

    2 publications · 64 citations

    2

    h-index

  3. HG
    H. G. Prentice

    University College London, United Kingdom

    2 publications · 64 citations

    2

    h-index

  4. MA
    Marlene A. Jacobson

    United States Military Academy, United States

    2 publications · 74 citations

    2

    h-index

  5. MR
    Michael R. Blackburn

    The University of Texas Health Science Center at Houston, United States

    2 publications · 74 citations

    2

    h-index

1–5 of 173

Institutions

57

  1. University of Michigan

    Ann Arbor, United States

    3 h-index

    7 publications

    429 citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    8 publications

    3K citations

  3. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    2 h-index

    8 publications

    296 citations

  4. The Royal Free Hospital

    London, United Kingdom

    2 h-index

    14 publications

    448 citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    12 publications

    29.5K citations

  6. University of Copenhagen

    Copenhagen, Denmark

    2 h-index

    5 publications

    365 citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    3 publications

    150 citations

  8. Tel Aviv University

    Tel Aviv, Israel

    2 h-index

    8 publications

    163 citations

1–8 of 57

Venues

  1. Journal of Biological Chemistry

    JBC · 8 publications · 815 citations

    8

    h-index

  2. Biochemistry

    4 publications · 133 citations

    4

    h-index

  3. Nucleic Acids Research

    3 publications · 214 citations

    3

    h-index

  4. PubMed

    Repository · 2 publications · 179 citations

    2

    h-index

  5. Journal of Clinical Investigation

    JCI · 2 publications · 74 citations

    2

    h-index

1–5