Concepedia

Darpin Engineering

Darpin Engineering is a protein scaffold engineering method that involves the rational design and selection of engineered ankyrin repeat proteins to achieve high-affinity, specific binding interactions with target molecules.

26

Publications

1.3K

Citations

153

Authors

54

Institutions

Publications per year

2017–2026

13

Parents

Publications

26

Designed Ankyrin Repeat Proteins (DARPins)

Rastislav Tamaskovic, Manuel Simon, Nikolas Stefan et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 2012 · 119 citations

, , +11

DARPins: An Efficient Targeting Domain for Lentiviral Vectors

Robert C. Münch, Michael D. Mühlebach, Thomas Schaser et al. · Molecular Therapy · 2011 · 115 citations · Full text

, , +14

Bispecific Designed Ankyrin Repeat Proteins (DARPins) Targeting Epidermal Growth Factor Receptor Inhibit A431 Cell Proliferation and Receptor Recycling

Ykelien L. Boersma, Daniel Steiner, K. Dane Wittrup et al. · Journal of Biological Chemistry · 2011 · 109 citations · Full text

, , +13

Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry

Michael Brauchle, Simon Hansen, Emmanuel Caussinus et al. · Biology Open · 2014 · 96 citations · Full text

, , +17

Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging

Robert M. Goldstein, Jane Sosabowski, Maria Livanos et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2014 · 90 citations · Full text

, , +17

1–5 of 26

Authors

153

  1. AP
    Andreas Plückthun

    University of Zurich, Switzerland

    15 publications · 956 citations

    13

    h-index

  2. FB
    Fabian Brandl

    University of Regensburg, Germany

    3 publications · 108 citations

    3

    h-index

  3. UZ
    Uwe Zangemeister‐Wittke

    University Hospital of Zurich, Switzerland

    3 publications · 191 citations

    3

    h-index

  4. CJ
    Christian J. Buchholz

    Paul Ehrlich Institut, Germany

    3 publications · 197 citations

    3

    h-index

  5. MS
    Manuel Simon

    University of Vienna, Austria

    3 publications · 249 citations

    3

    h-index

1–5 of 153

Institutions

54

  1. University of Zurich

    Zurich, Switzerland

    13 h-index

    70 publications

    3.9K citations

  2. University of Basel

    Basel, Switzerland

    3 h-index

    12 publications

    579 citations

  3. Paul Ehrlich Institut

    Langen, Germany

    3 h-index

    17 publications

    1.1K citations

  4. University of Bern

    Bern, Switzerland

    3 h-index

    6 publications

    382 citations

  5. ETH Zurich

    Zurich, Switzerland

    2 h-index

    6 publications

    181 citations

  6. SLAC National Accelerator Laboratory

    Menlo Park, United States

    2 h-index

    2 publications

    113 citations

  7. University Hospital of Bern

    Bern, Switzerland

    2 h-index

    6 publications

    182 citations

  8. University of Pennsylvania

    Philadelphia, United States

    1 h-index

    9 publications

    414 citations

1–8 of 54

Venues

  1. Journal of Biological Chemistry

    JBC · 2 publications · 154 citations

    2

    h-index

  2. Biology Open

    BiO · 2 publications · 109 citations

    2

    h-index

  3. Human Gene Therapy

    2 publications · 90 citations

    2

    h-index

  4. Bioconjugate Chemistry

    2 publications · 130 citations

    2

    h-index

  5. Scientific Reports

    2 publications · 113 citations

    2

    h-index

1–5