Concepedia

Cyclooctyne Probes

Cyclooctyne Probes is a class of bioorthogonal reagents that enables fluorogenic labeling of biomolecules through strain-promoted alkyne-azide cycloaddition, distinguished by its ring strain-activated reactivity in the absence of catalysts.

51

Publications

6.1K

Citations

242

Authors

93

Institutions

Publications per year

2017–2026

17

Parents

Publications

51

Copper-free click chemistry for dynamic <i>in vivo</i> imaging

Jeremy M. Baskin, Jennifer A. Prescher, Scott T. Laughlin et al. · Proceedings of the National Academy of Sciences · 2007 · 1.8K citations · Full text

, , +17

Copper-free click chemistry in living animals

Pamela V. Chang, Jennifer A. Prescher, Ellen M. Sletten et al. · Proceedings of the National Academy of Sciences · 2010 · 645 citations · Full text

, , +15

Genetic Encoding of Bicyclononynes and <i>trans</i>-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

Kathrin Lang, Lloyd Davis, Stephen Wallace et al. · Journal of the American Chemical Society · 2012 · 524 citations · Full text

, , +13

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/ <i>trans</i> ‐Cyclooctene Cycloaddition

Neal K. Devaraj, Rabi Upadhyay, Jered B. Haun et al. · Angewandte Chemie International Edition · 2009 · 372 citations · Full text

, , +17

A Hydrophilic Azacyclooctyne for Cu-Free Click Chemistry

Ellen M. Sletten, Carolyn R. Bertozzi · Organic Letters · 2008 · 283 citations · Full text

, , +14

1–5 of 51

Authors

242

  1. CR
    Carolyn R. Bertozzi

    Howard Hughes Medical Institute, United States

    8 publications · 3.2K citations

    8

    h-index

  2. JM
    Joseph M. Fox

    University of Delaware, United States

    4 publications · 820 citations

    4

    h-index

  3. RW
    Ralph Weissleder

    Massachusetts General Hospital, United States

    3 publications · 517 citations

    3

    h-index

  4. JA
    Jennifer A. Prescher

    University of California, Irvine, United States

    3 publications · 2.5K citations

    3

    h-index

  5. EA
    Edward A. Lemke

    European Molecular Biology Laboratory, Germany

    3 publications · 132 citations

    3

    h-index

1–5 of 242

Institutions

93

  1. University of California, Berkeley

    Berkeley, United States

    7 h-index

    25 publications

    17K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    20 publications

    5.8K citations

  3. University of Delaware

    Newark, United States

    4 h-index

    12 publications

    2K citations

  4. Massachusetts General Hospital

    Boston, United States

    3 h-index

    13 publications

    2.5K citations

  5. HUN-REN Research Centre for Natural Sciences

    Budapest, Hungary

    3 h-index

    17 publications

    710 citations

  6. Center for Systems Biology

    Boston, United States

    3 h-index

    13 publications

    2.5K citations

  7. Institute of Molecular and Cell Biology

    Novosibirsk, Russia

    3 h-index

    3 publications

    2.6K citations

  8. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    4 publications

    3K citations

1–8 of 93

Venues

  1. Chemical Communications

    ChemComm · 7 publications · 431 citations

    7

    h-index

  2. Bioconjugate Chemistry

    6 publications · 278 citations

    6

    h-index

  3. Angewandte Chemie International Edition

    5 publications · 633 citations

    5

    h-index

  4. Chemistry - A European Journal

    4 publications · 139 citations

    4

    h-index

  5. Angewandte Chemie

    4 publications · 129 citations

    4

    h-index

1–5