Cumulative Dose Effects
Cumulative Dose Effects is a pharmacological risk construct that denotes the progressive, dose-dependent decline in cardiac function observed with increasing total exposure to cardiotoxic anticancer agents over the course of therapy.
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512
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2017–2026
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Congestive heart failure in patients treated with doxorubicin
Sandra M. Swain, Fredrick S. Whaley, Michael S. Ewer · Cancer · 2003 · 2.3K citations · Full text
Medicine, Oncology, Pharmacology +15
Reproducibility and comparison of responses to inhaled histamine and methacholine.
E. F. Juniper, Peter Frith, Charles W. Dunnett et al. · Thorax · 1978 · 548 citations · Full text
Medicine, Pharmacology, Allergy +9
Phase II evaluation of adriamycin in human neoplasia
Robert M. OʼBryan, James K. Luce, Robert W. Talley et al. · Cancer · 1973 · 417 citations · Full text
Medicine, Oncology, Pharmacology +14
Dose response evaluation of adriamycin in human neoplasia
Laurence H. Baker, Josh Gottlieb, Saul E. Rivkin et al. · Cancer · 1977 · 386 citations · Full text
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Johns Hopkins University
Baltimore, United States
5 h-index
14 publications
1.6K citations

University of British Columbia
Vancouver, Canada
4 h-index
14 publications
2K citations
New York University
New York, United States
4 h-index
13 publications
1.8K citations
Institut de Radioprotection et de Sûreté Nucléaire
Fontenay-aux-Roses, France
4 h-index
9 publications
330 citations

McGill University
Montreal, Canada
4 h-index
12 publications
1K citations

University of Toronto
Toronto, Canada
4 h-index
12 publications
866 citations
United States Food and Drug Administration
Silver Spring, United States
3 h-index
3 publications
183 citations

Karolinska Institutet
Stockholm, Sweden
3 h-index
6 publications
587 citations
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Repository · 17 publications · 781 citations
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