Cryptic Binding Pockets is a structural phenomenon in proteins characterized by transient, often concealed ligand-binding sites that are not evident in the protein's dominant conformational state but become accessible through conformational rearrangements induced by ligand binding or dynamic fluctuations.
78
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6.2K
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349
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152
Institutions
Publications per year
2017–2026
53
Variants
Cryptic Pockets
Parents
Publications
78
Stretching Single Talin Rod Molecules Activates Vinculin Binding
Armando E. del Río Hernández, Raúl Pérez‐Jiménez, Ruchuan Liu et al. · Science · 2009 · 1.5K citations · Full text
1–5 of 78
Authors
349
- GR
11
h-index
- MD
7
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- JB
7
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6
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- AM
6
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1–5 of 349
Institutions
152
Washington University in St. Louis
St Louis, United States
11 h-index
65 publications
6.5K citations
National University of Singapore
Singapore, Singapore
7 h-index
27 publications
9.6K citations
Agency for Science, Technology and Research
Singapore, Singapore
5 h-index
18 publications
442 citations
Bioinformatics Institute
Singapore, Singapore
5 h-index
18 publications
442 citations
University College London
London, United Kingdom
5 h-index
15 publications
1.1K citations
Living Systems (United States)
Saint Albans, United States
5 h-index
34 publications
4.2K citations
Institute of Structural and Molecular Biology
London, United Kingdom
4 h-index
6 publications
819 citations
University of Washington
Seattle, United States
4 h-index
18 publications
1.5K citations
1–8 of 152
Venues
- Journal of Chemical Theory and Computation
JCTC · 9 publications · 409 citations
9
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- Journal of Chemical Information and Modeling
JCIM · 8 publications · 348 citations
8
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- bioRxiv (Cold Spring Harbor Laboratory)
Repository · 6 publications · 140 citations
6
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- Scientific Reports
4 publications · 118 citations
4
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- Journal of Molecular Biology
JMB · 4 publications · 669 citations
4
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1–5