Concepedia

Cryo-electron Microscopy Interpretation

Cryo-Electron Microscopy Interpretation is a computational and analytical framework used in structural biology to derive high-resolution three-dimensional models of macromolecular complexes from electron density maps generated by cryo-electron microscopy, distinguished by its integration of image processing algorithms, biochemical knowledge, and structural constraints to assign biological function to observed morphologies.

148

Publications

12.4K

Citations

617

Authors

223

Institutions

Publications per year

2017–2026

79

Parents

Publications

148

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

Nature Methods · 2019 · 1.7K citations · Full text

, , +10

New tools for automated cryo-EM single-particle analysis in RELION-4.0

Dari Kimanius, Liyi Dong, Grigory Sharov et al. · Biochemical Journal · 2021 · 1.2K citations · Full text

, , +17

Adding the Third Dimension to Virus Life Cycles: Three-Dimensional Reconstruction of Icosahedral Viruses from Cryo-Electron Micrographs

Timothy S. Baker, Norman H. Olson, S.D. Fuller · Microbiology and Molecular Biology Reviews · 2000 · 478 citations

, , +17

Convolutional neural networks for automated annotation of cellular cryo-electron tomograms

Muyuan Chen, Wei Dai, Stella Sun et al. · Nature Methods · 2017 · 441 citations · Full text

, , +16

Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions

Lisa Craig, Niels Volkmann, A.S. Arvai et al. · Molecular Cell · 2006 · 416 citations · Full text

, , +16

1–5 of 148

Authors

617

  1. WC
    Wah Chiu

    Baylor College of Medicine, United States

    8 publications · 667 citations

    8

    h-index

  2. TC
    Thomas C. Terwilliger

    Los Alamos National Laboratory, United States

    6 publications · 362 citations

    6

    h-index

  3. PD
    Paul D. Adams

    Lawrence Berkeley National Laboratory, United States

    5 publications · 227 citations

    5

    h-index

  4. SH
    Sjors H. W. Scheres

    MRC Laboratory of Molecular Biology, United Kingdom

    5 publications · 1.5K citations

    5

    h-index

  5. PV
    Pavel V. Afonine

    Lawrence Berkeley National Laboratory, United States

    5 publications · 227 citations

    5

    h-index

1–5 of 617

Institutions

223

  1. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    8 h-index

    17 publications

    5.6K citations

  2. University of Missouri

    Columbia, United States

    7 h-index

    19 publications

    912 citations

  3. Lawrence Berkeley National Laboratory

    Berkeley, United States

    7 h-index

    21 publications

    957 citations

  4. Scripps Research Institute

    San Diego, United States

    6 h-index

    25 publications

    3.5K citations

  5. New Mexico Consortium

    Los Alamos, United States

    6 h-index

    6 publications

    362 citations

  6. Baylor College of Medicine

    Houston, United States

    6 h-index

    28 publications

    4K citations

  7. Centro Nacional de Biotecnología

    Madrid, Spain

    6 h-index

    18 publications

    472 citations

  8. Purdue University West Lafayette

    West Lafayette, United States

    6 h-index

    12 publications

    1.8K citations

1–8 of 223

Venues

  1. Journal of Structural Biology

    17 publications · 889 citations

    17

    h-index

  2. Journal of Molecular Biology

    JMB · 10 publications · 785 citations

    10

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 6 publications · 103 citations

    8

    h-index

  4. Structure

    7 publications · 268 citations

    7

    h-index

  5. Ultramicroscopy

    6 publications · 652 citations

    6

    h-index

1–5