Concepedia

Cross-exon Interactions

Cross-Exon Interactions is a molecular mechanism in pre-mRNA splicing whereby spliceosomal components and regulatory proteins bridge exons across intron boundaries to facilitate exon recognition and accurate splice site pairing during the process of exon definition.

32

Publications

2.6K

Citations

142

Authors

79

Institutions

Publications per year

2017–2026

6

Parents

Publications

32

A role for exon sequences and splice-site proximity in splice-site selection

Robin Reed, Tom Maniatis · Cell · 1986 · 480 citations

, , +11

The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on mRNA

Fulvia Bono, J. Ebert, Esben Lorentzen et al. · Cell · 2006 · 424 citations · Full text

, , +15

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

Hala Chamieh, Lionel Ballut, Fabien Bonneau et al. · Nature Structural & Molecular Biology · 2007 · 345 citations

, , +15

The Y14 protein communicates to the cytoplasm the position of exon–exon junctions

V. Narry Kim · The EMBO Journal · 2001 · 178 citations · Full text

, , +9

RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons

James D. Thomas, Jacob T. Polaski, Qing Feng et al. · Nature Genetics · 2020 · 137 citations · Full text

, , +14

1–5 of 32

Authors

142

  1. JD
    Jean D. Beggs

    University of Edinburgh, United Kingdom

    3 publications · 232 citations

    3

    h-index

  2. ID
    Ian Dix

    University of Edinburgh, United Kingdom

    2 publications · 121 citations

    2

    h-index

  3. AJ
    Andrew J. Newman

    MRC Laboratory of Molecular Biology, United Kingdom

    2 publications · 121 citations

    2

    h-index

  4. HU
    Henning Urlaub

    Max Planck Institute for Biophysical Chemistry, Germany

    2 publications · 49 citations

    2

    h-index

  5. RL
    Reinhard Lührmann

    Max Planck Institute for Biophysical Chemistry, Germany

    2 publications · 49 citations

    2

    h-index

1–5 of 142

Institutions

79

  1. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    3 h-index

    5 publications

    353 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    8 publications

    1.1K citations

  3. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    9 publications

    1.1K citations

  4. University of Massachusetts Chan Medical School

    Worcester, United States

    2 h-index

    3 publications

    101 citations

  5. University of Manchester

    Manchester, United Kingdom

    2 h-index

    2 publications

    121 citations

  6. Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa

    Cape Town, South Africa

    2 h-index

    3 publications

    163 citations

  7. University of Edinburgh

    Edinburgh, United Kingdom

    2 h-index

    6 publications

    363 citations

  8. Fred Hutch Cancer Center

    Seattle, United States

    2 h-index

    12 publications

    1.5K citations

1–8 of 79

Venues

  1. RNA

    4 publications · 148 citations

    4

    h-index

  2. The EMBO Journal

    3 publications · 284 citations

    3

    h-index

  3. Genomics

    2 publications · 43 citations

    2

    h-index

  4. Cell

    2 publications · 904 citations

    2

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 2 publications · 56 citations

    2

    h-index

1–5