Concepedia

Core Scaffold Libraries

Core Scaffold Libraries is a methodological construct in medicinal chemistry that refers to a systematically curated collection of molecular frameworks serving as foundational templates for the generation of structurally diverse compounds in scaffold diversification efforts.

69

Publications

2.7K

Citations

468

Authors

144

Institutions

Publications per year

2017–2026

24

Parents

Publications

69

Biology-Oriented Synthesis: Harnessing the Power of Evolution

Hilde van Hattum, Herbert Waldmann · Journal of the American Chemical Society · 2014 · 244 citations

, , +17

Structure-Based Design, Synthesis, and Antimicrobial Activity of Indazole-Derived SAH/MTA Nucleosidase Inhibitors

Xiaoming Li, Sam Chu, Victoria A. Feher et al. · Journal of Medicinal Chemistry · 2003 · 160 citations · Full text

, , +16

Facile access to nitroarenes and nitroheteroarenes using N-nitrosaccharin

Roxan Calvo, Kun Zhang, Alessandro Passera et al. · Nature Communications · 2019 · 121 citations · Full text

, , +12

Recent Developments in the Stereocontrolled Synthesis of Highly Substituted Cyclopentane Core Structures: From Drug Discovery Research to Natural Product Synthesis

Brian Heasley · Current Organic Chemistry · 2014 · 97 citations

, , +13

The concept of privileged structures in rational drug design: focus on acridine and quinoline scaffolds in neurodegenerative and protozoan diseases

Salvatore Bongarzone, María Laura Bolognesi · Expert Opinion on Drug Discovery · 2011 · 90 citations

, , +16

1–5 of 69

Authors

468

  1. MN
    Michaïl N. Elinson

    N.D. Zelinsky Institute of Organic Chemistry, Russia

    3 publications · 75 citations

    3

    h-index

  2. MP
    Mikhail P. Egorov

    N.D. Zelinsky Institute of Organic Chemistry, Russia

    3 publications · 75 citations

    3

    h-index

  3. AN
    A. N. Vereshchagin

    N.D. Zelinsky Institute of Organic Chemistry, Russia

    3 publications · 75 citations

    3

    h-index

  4. UH
    Uwe H. F. Bunz

    Heidelberg University, Germany

    2 publications · 54 citations

    2

    h-index

  5. AS
    Alexander S. Goloveshkin

    A. N. Nesmeyanov Institute of Organoelement Compounds, Russia

    2 publications · 54 citations

    2

    h-index

1–5 of 468

Institutions

144

  1. N.D. Zelinsky Institute of Organic Chemistry

    Moscow, Russia

    3 h-index

    16 publications

    416 citations

  2. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    3 h-index

    9 publications

    752 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    20 publications

    430 citations

  4. Korea Institute of Science and Technology

    Seoul, South Korea

    2 h-index

    6 publications

    348 citations

  5. A. N. Nesmeyanov Institute of Organoelement Compounds

    Moscow, Russia

    2 h-index

    3 publications

    95 citations

  6. University of Copenhagen

    Copenhagen, Denmark

    2 h-index

    6 publications

    117 citations

  7. Wellcome Trust

    London, United Kingdom

    2 h-index

    2 publications

    114 citations

  8. TU Dortmund University

    Dortmund, Germany

    2 h-index

    4 publications

    292 citations

1–8 of 144

Venues

  1. Journal of Medicinal Chemistry

    7 publications · 424 citations

    7

    h-index

  2. Bioorganic & Medicinal Chemistry Letters

    6 publications · 96 citations

    6

    h-index

  3. Organic Letters

    OL · 5 publications · 160 citations

    5

    h-index

  4. Bioorganic & Medicinal Chemistry

    5 publications · 166 citations

    5

    h-index

  5. European Journal of Medicinal Chemistry

    4 publications · 162 citations

    4

    h-index

1–5