Concepedia

Copy Number Optimization

Copy Number Optimization is a computational method used in synthetic biology to minimize metabolic burden in engineered organisms by fine-tuning the number of gene copies to achieve optimal expression without compromising cellular fitness.

119

Publications

10.7K

Citations

630

Authors

208

Institutions

Publications per year

2017–2026

47

Parents

Publications

119

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

Nils A. Kulak, Garwin Pichler, Igor Paron et al. · Nature Methods · 2014 · 1.8K citations

, , +14

Specific-purpose plasmid cloning vectors II. Broad host range, high copy number, RSF 1010-derived vectors, and a host-vector system for gene cloning in Pseudomonas

Michael Bagdasarian, R. Lurz, Beate Rückert et al. · Gene · 1981 · 1.1K citations

, , +17

A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly

Michael E. Lee, William C. DeLoache, Bernardo Cervantes et al. · ACS Synthetic Biology · 2015 · 1K citations · Full text

, , +13

Scrutinizing key steps for reliable metabarcoding of environmental samples

Antton Alberdi, Ostaizka Aizpurua, M. Thomas P. Gilbert et al. · Methods in Ecology and Evolution · 2017 · 746 citations · Full text

, , +13

The Mouse Universal Genotyping Array: From Substrains to Subspecies

Andrew P. Morgan, Chen-Ping Fu, Chia-Yu Kao et al. · G3 Genes Genomes Genetics · 2015 · 267 citations · Full text

, , +17

1–5 of 119

Authors

630

  1. EK
    Eric Klavins

    University of Washington, United States

    2 publications · 41 citations

    2

    h-index

  2. SA
    Samuel A. Burden

    University of Washington, United States

    2 publications · 41 citations

    2

    h-index

  3. NN
    Nils Napp

    University at Buffalo, State University of New York, United States

    2 publications · 41 citations

    2

    h-index

  4. SK
    Sang Ki Rhee

    Korea Research Institute of Bioscience and Biotechnology, South Korea

    2 publications · 104 citations

    2

    h-index

  5. HA
    Hyun Ah Kang

    Chung-Ang University, South Korea

    2 publications · 104 citations

    2

    h-index

1–5 of 630

Institutions

208

  1. University of California, Berkeley

    Berkeley, United States

    7 h-index

    18 publications

    4.7K citations

  2. East China University of Science and Technology

    Shanghai, China

    5 h-index

    23 publications

    1.4K citations

  3. University of Illinois Urbana-Champaign

    Urbana, United States

    5 h-index

    11 publications

    773 citations

  4. Jiangnan University

    Wuxi, China

    4 h-index

    21 publications

    1.4K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    17 publications

    1.9K citations

  6. University of California San Diego

    San Diego, United States

    4 h-index

    8 publications

    655 citations

  7. Shandong University

    Jinan, China

    3 h-index

    11 publications

    680 citations

  8. Zhejiang University

    Hangzhou, China

    3 h-index

    8 publications

    150 citations

1–8 of 208

Venues

  1. Journal of Agricultural and Food Chemistry

    8 publications · 422 citations

    9

    h-index

  2. Gene

    7 publications · 2K citations

    7

    h-index

  3. ACS Synthetic Biology

    7 publications · 1.2K citations

    7

    h-index

  4. Nucleic Acids Research

    6 publications · 363 citations

    6

    h-index

  5. Biotechnology and Bioengineering

    4 publications · 231 citations

    5

    h-index

1–5